MagNA Pure Systems and Nucleic Acid Purification Reagents

Automated nucleic acid purification solutions let you unlock what's next with confidence

Roche Nucleic Acid Purification

Workflow and throughput solutions for your lab

MagnaPure 96 for Nucleic Acid Purification

MagNA Pure 96 System
1-96 samples in one hour

MagNA Pure 24 System
1-24 samples in 70 min

High Pure Kits
Manual Extraction

MagNA Pure LC 2.0 for Nucleic Acid Purification

MagNA Pure LC 2.0 System
1-32 samples in one hour

MagNA Pure Compact System for nucleic acid purification

MagNA Pure Compact System
1-8 samples in one hour

Discover the right solution for you

Your genomic workflow begins with nucleic acid purification. Start confidently and increase your workflow efficiency with Roche manual and automated solutions. Use the table below to guide your next nucleic acid extraction.

	Automated Extraction				Manual Extraction
	MagNA Pure 96 System**	MagNA Pure 24 System**	MagNA Pure LC 2.0 System*	MagNA Pure Compact System*	High Pure Kits
# of Samples	1-96 samples per run	1-24 samples per run	1-32 samples per run	1-8 samples per run	Up to 250 isolations per kit
Run Time	~1 hour	~70 min	~1 hour	~30 min	Less than 20 min
Starting Samples	Whole Blood, Plasma, Serum, Cell Culture, Tissue, Body Fluids, Fresh Frozen and FFPE Tissue, Swab, Stool, Sputum
Nucleic Acid Targets	Genomic and Bacterial DNA, Viral DNA/RNA, Plasmid DNA and Total RNA

* For general laboratory use
** For in vitro diagnostic use

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MagNA Pure 96 System

Designed for an accelerated workflow

The MagNA Pure 96 System is optimized for high-throughput nucleic acid purification – 96 samples extracted in less than one hour. Requiring minimal setup with the help of prefilled reagent kits, preloaded protocols for a broad range of sample types, and deck surveillance, the MagNA Pure 96 maximizes productivity and dramatically reduces handling errors.

For in vitro diagnostic use.

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MagNA Pure 96 Nucleic Acid Purification System Protocols

MagNA Pure 96 Protocols

Available for Download

The MagNA Pure 96 System has new and improved protocols. Now optimised for use in sequencing, the MagNA Pure Systems can ensure reliable sequencing results from the start.

Learn More

MagNA Pure 96 Reagents
MagNA Pure 96 Consumables
MagNA Pure 96 Accessories
MagNA Pure 96 Software

MagNA Pure 96 Reagents

	# of Isolations	Target	Starting Material										Product No.
	# of Isolations	Target	Whole Blood	Plasma	Cell Culture	Serum	Body Fluids	Fresh Frozen Tissue	FFPE Tissue	Swab	Stool	Sputum	Product No.
MagNA Pure 96 DNA and Viral Nucleic Acid Small Volume Kit	3x192 (200 µL)	Genomic DNA	X		X			X	X				06543588001
		Bacterial DNA	X	X	X	X	X			X	X	X
		Viral DNA/RNA	X	X	X	X	X			X	X	X
MagNA Pure 96 DNA and Viral Nucleic Acid Large Volume Kit	3x96 (0.5 mL) 3x48 (1 mL)	Cell-free NA		X									06374891001
		Genomic DNA	X		X			X
		Bacterial DNA	X	X	X	X	X			X	X	X
		Viral RNA/DNA	X	X	X	X	X			X	X	X
MagNA Pure 96 Cellular RNA Large Volume Kit *	3x96 or 3x48	Total RNA	X		X			X	X				05467535001
X: Roche Supported Protocols

Lysis Buffer	Pack Size	Description	Product No.
MagNA Pure cfNA Buffer set	upto 96 isolations	External lysis buffer to enable the isolation of cell-free nucleic acid (cfNA)	07794398001
MagNA Pure 96 External Lysis Buffer	100 mL	External lysis buffer for Whole Blood, Plasma and Serum samples	06374913001
MagNA Pure 96 Bacterial Lysis Buffer	20 mL	External lysis buffer for various sample types with bacterial and viral targets	06374921001
MagNA Pure 96 DNA Tissue Lysis Buffer	100 mL	External lysis buffer for Tissue samples (FFPE and Fresh Frozen)	06640702001
S.T.A.R. Buffer (Stool Transport and Recovery)†	100 mL	External lysis buffer for Whole Blood, Plasma and Serum samples	03335208001

MagNA Pure 96 Consumables

Consumables for the MagNA Pure 96	Pack Size	Description	Product No.
MagNA Pure 96 Processing Cartridge	36 cartridges	Sample Input and extraction processing deep well plate	06241603001
MagNA Pure 96 Output Plate	60 plates	Eluate Collection plate	06241611001
MagNA Pure Tip 1000 µL	3,840 filter tips	Disposable tips (1000 µL) with aerosol filters	06241620001
MagNA Pure Sealing Foil	100 foils	Foils for sealing of reagent trays, output plate and processing cartridge	06241638001
MagNA Pure 96 Internal Control Tube	150 tubes	Barcoded tubes for automated processing of internal controls	06374905001

MagNA Pure 96 Accessories

Accessories for the MagNA Pure 96	Pack Size	Description	Product No.
MagNA Pure 96 Drop Catcher	10 drop catchers	Replacement accessory for MagNA Pure 96 maintenance and cleaning	06541119001
MagNA Pure 96 Reagent Loop Unit	1 reagent loop	MagNA Pure 96 Reagent Loop Unit for replacement	06541127001
MagNA Pure 96 Barcode Scanner	1 barcode scanner	MagNA Pure 96 Barcode Scanner for Replacement	06541143001
MagNA Pure 96 Tip Rack	1 tip rack	MagNA Pure 96 Tip Rack for Replacement	06541151001
MagNA Pure 96 Bottle Rack	1 bottle rack	MagNA Pure 96 Bottle Rack for Replacement	06541178001
MagNA Pure 96 Needle Set of 4	1 set	4 Needles/Set, MagNA Pure 96 reagent pipetting head needles for replacement	06541194001
MagNA Pure 96 Purification Rack	1 purification rack	MagNA Pure 96 Purification Rack for replacement	06541208001
MagNA Pure 96 Reagent Rack	1 reagent rack	MagNA Pure 96 Reagent Rack for Replacement	06541224001
MagNA Pure 96 Waste Rack	1 waste rack	MagNA Pure 96 Waste Rack for Replacement	06541259001
MagNA Pure 96 Internal Waste Container	1 waste container	MagNA Pure 96 Internal Waste Container for replacement	06541267001
MagNA Pure 96 Waste Cover	1 waste cover	MagNA Pure 96 Waste Cover for replacement	06541275001
MagNA Pure 96 Plate Holder	1 plate holder	Plate holder for predefined custom plates as mentioned in the Operator's	06541283001
MagNA Pure 96 LightCycler^® 480 Adapter	1 adapter	Adapter plate for Support of LightCycler^® 480 Multiwell Plate	06638996001
MagNA Pure 96 Archive Plate Adapter 4S	1 adapter	Adapter plate for Support of 96-well plates with non-snap-lock tubes	06639003001

MagNA Pure 96 Software

The MagNA Pure 96 System is currently on software version 3.0.1. All purification and PCR Setup protocols are updated with this current software. If a software version earlier than v3.0.1 is installed on your MagNA Pure 96 Instrument, please contact Roche to set up a visit by a Roche service engineer.

MagNA Pure 24 System

Enter a new world of productivity

The MagNA Pure 24 System is a fully-automated clinical nucleic acid extraction system that brings you walkaway automation, designed to minimize user intervention and extraction-to–extraction variability. In addition to providing quality purified eluates, the MagNA Pure 24 System offers onboard primary-sample handling and mixed-batch sampling for up to 24 samples per run.

For in vitro diagnostic use.

Learn More

MagNA Pure 24 Product Video

See it in action

Start here. Go anywhere.

For years, molecular testing laboratories have trusted the MagNA Pure family to dramatically reduce handling errors with reliable and simplified sample preparation. Building on this legacy, discover the MagNA Pure 24 System by traveling inside to follow a sample’s journey and see how you can be confident from start to finish.

MagNA Pure 24 Nucleic Acid Purification System Protocols

MagNA Pure 24 Protocols

Available for Download

The MagNA Pure 24 System has new and improved protocols. Now optimised for use in sequencing, the MagNA Pure Systems can ensure reliable sequencing results from the start.

Learn More

MagNA Pure 24 Reagents
MagNA Pure 24 Consumables
MagNA Pure 24 Accessories
MagNA Pure 24 Software

MagNA Pure 24 Reagents

The MagNA Pure 24 Total Nucleic Acid Kit eliminates unnecessary complexity by enabling extraction of nucleic acids from 10 different sample types with one simple reagent kit. It is sealable for later use, barcoded for inventory tracking, and compatible with a multitude of external lysis buffer to expand the range of applications.

	# of Isolations	Target	Starting Material								Product No.
	# of Isolations	Target	Whole Blood	Plasma	Serum	Fresh Frozen Tissue	Urine	Stool	Others*	Cultured Cells	Product No.
MagNA Pure 24 Total NA Isolation Kit**	96 small volume (200 µL)	Genomic DNA and bacterial, fungal or viral NA	X	X	X	X (up to 5 mg)	X	X	X	X (up to 10⁵ cultured cells)	07658036001
	72 large volume (500 µL, 1000 µL)	Genomic DNA and bacterial, fungal or viral NA	X	X	X		X	X	X	X (up to 10⁶ cultured cells)
	72 extra large volume (2000 µL, 4000 µL)	Human cell-free nucleic acid		X
X: Roche Supported Protocols
*Other human sample types include Bronchoalveolar lavage, and Swab (nasopharyngeal, cervical).

** MagNA Pure 24 Total NA Isolation Kit is for in vitro diagnostic use.

Additional Reagents or Lysis Buffers	Pack Size	Description	Product No.
MagNA Pure 24 MGP Set	12 tubes	Additional magnetic glass particles for isolations of nucleic acids. Single use	07806361001
MagNA Pure cfNA Buffer Set	Up to 96 isolations	For the isolation of cell-free nucleic acids from plasma samples	07794398001
MagNA Pure LC Total Nucleic Acid Isolation Kit – Lysis/Binding Buffer Refill	100 mL	For external lysis protocols	03246779001
MagNA Pure Bacteria Lysis Buffer	20 mL	For the isolation of bacterial, fungal, and viral nucleic acids	04659180001
MagNA Pure DNA Tissue Lysis Buffer	100 mL	For the isolation of nucleic acids from fresh frozen tissue	04805160001
S.T.A.R. Buffer (Stool Transport and Recovery Buffer)	100 mL	For stabilization, transport and recovery of nucleic acids in stool samples	03335208001

Additional Reagents and Lysis Buffers are for general laboratory use unless otherwise noted.

MagNA Pure 24 MGP Set is for in vitro diagnostic use.

MagNA Pure 24 Consumables

Consumables for the MagNA Pure 24 System	Pack Size	Description	Product No.
MagNA Pure 24 Processing Cartridge	48 cartridges	Allows processing of 8 samples in parallel and holds pipetted samples and reagents during processing	07345577001
MagNA Pure 24 Tip Park - Piercing Tool	48 processing tip parks and 50 piercing tools	Holds pipette tips used for sample pipetting and processing into the processing station adapter during a run	07345585001
MagNA Pure 24 Piercing Tool	50 piercing tools	Used to pierce sealed reagent cassettes in order to enable reagent pipetting	07534205001
MagNA Pure Tip 1000 µL	40 x 96 tips	Disposable tips (1000 µL) with aerosol filters	06241620001
Tip CORE TIPS with Filter, 50 µL **	60 x 96 tips	Disposable tips (50 µL) with aerosol filters	07102127001
MagNA Pure Sealing Foil **	100 foils	Foils for sealing of reagent trays, output plate and processing cartridge	06241638001
MagNA Pure Tube 2.0 mL **	350 (10 x 35) tubes	Barcoded tubes used as secondary tubes, user-defined internal control tubes, and output tubes	07857551001
FrameStrip^® with flat caps - Low profile **	120 tube strips 300 cap strips	8-tube strips to collect and store eluates of up to 50 μL. Also compatible with the LightCycler^® 480 and LightCycler^® 96 real-time PCR Systems	07345593001
FrameStrip^® with flat caps - High profile **	120 tube strips 300 cap strips	8-tube strips to collect and store eluates of up to 150 μL	07652275001

Consumables are for in vitro diagnostic use unless otherwise noted.

** For General Laboratory Use

MagNA Pure 24 Accessories

Accessories for MagNA Pure 24 System	Pack Size	Description	Product No.
MagNA Pure 24 Reagent Rack	1 reagent rack	Rack to load reagents (such as MGP) onto the instrument	07930836001
MagNA Pure 24 Sample Rack	1 sample rack	Holds up to 24 sample tubes (primary tubes with 13-16.2 mm outer diameter)	07930852001
MagNA Pure 24 Sample Rack Adapter	1 rack with 24 adapters	Holds up to 24 sample tubes and comes with 24 sample tube adapters (primary tubes or MagNA Pure Tubes 2.0 mL)	07931123001
MagNA Pure 24 Processing Station Adapter	3 processing station adapters	Processing station adapter for MagNA Pure 24 Processing Cartridge, MagNA Pure 24 Tip Park, and MagNA Pure 24 Liquid Waste Insert	07931212001
MagNA Pure 24 Tip Waste Container	1 tip waste container	Tip waste container	07930828001
MagNA Pure 24 Liquid Waste Insert	48 liquid waste inserts	Placed into the liquid waste reservoir of the processing station adapter to collect liquid waste. The liquid waste inserts can also be easily sealed for disposal if needed	07931182001
MagNA Pure 24 Reagent Tip Park	1 reagent tip park	Tip park for reagents	07931166001
MagNA Pure 24 Output Adapter 18mm	1 adapter	Loaded on the cooling station to hold 18-mm output consumable adapters (such as MagNA Pure Tubes 2.0mL)	07931131001
MagNA Pure 24 Output Adapter 9mm	1 adapter	Loaded on the cooling station to hold 9-mm output consumable adapters (such as 8-tube strips)	07931140001
MagNA Pure 24 Down Holder Frame	1 frame	Downholder frame for 8-tube strips (output consumables)	07931158001
MagNA Pure 24 Post Elution Adapter	1 adapter	Loads tubes and 8-tube strips used in post elution runs in the cooling station of the instrument	07931204001

All accessories are for in vitro diagnostic use.

MagNA Pure 24 Software

The MagNA Pure 24 System is currently on software version 1.0.

If you need assistance to update your system software, please contact your local Roche representative.

MagNA Pure LC 2.0 System

The legacy continues.

he MagNA Pure LC 2.0 System is a mid-throughput system built on the reliability of the MagNA Pure LC System technology. The same nucleic acid purity, reproducibility for downstream genomic workflows, and now with improved software, touchscreen interface and enhanced data management capabilities.

For general laboratory use.

Learn More

MagNA Pure LC 2.0 Reagents
MagNA Pure LC 2.0 Consumables
MagNA Pure LC 2.0 Accessories
MagNA Pure LC 2.0 Software

MagNA Pure LC 2.0 Reagents

	# of isolations	Target	Starting Material											Product No.
	# of isolations	Target	Whole Blood	Blood Cells	Plasma	Cell Culture	Serum	Body Fluids	Fresh Frozen Tissue	FFPE Tissue	Swab	Stool	Sputum	Product No.
MagNA Pure LC DNA Isolation Kit I (Blood, Blood Cell)	192	Genomic or Bacterial DNA	X	X		X								03003990001
MagNA Pure LC DNA Isolation Kit II (Tissue)	192								X	X				03186229001
MagNA Pure LC DNA Isolation Kit III (Bacteria, Fungi)	192					X		X			C	C	C	03264785001
MagNA Pure LC DNA Isolation Kit- Large Volume	288		X	X		X								03310515001
MagNA Pure LC Total NA Isolation Kit	192	Viral DNA/RNA	X		X		X							03038505001
MagNA Pure LC Total NA Isolation Kit- Large Volume	192				X		X							03264793001
MagNA Pure LC Total NA Isolation Kit- High Performance	288		X		X		X							05323738001
MagNA Pure LC RNA Isolation Kit III (Tissue)	192	Total RNA							X	X				03330591001
MagNA Pure LC RNA Isolation Kit- High Performance	192	Total RNA	X	X		X								03542394001
MagNA Pure Bacteria Lysis Buffer	20 mL	Lysis Buffer												04659180001
X : Roche Supported Protocols
C : Roche Supported Protocols in combination with the MagNA Pure Bacteria Lysis Buffer and DNA_Bacteria purification protocol

MagNA Pure LC 2.0 Consumables

Consumables for the MagNA Pure LC	Pack Size	Description	Product No.
MPLC Reagent Tub (large)	120 tubs	MagNA Pure LC Reagent tub with a capacity of 100 mL	03004040001
MPLC Reagent Tub (medium)	150 tubs	MagNA Pure LC Reagent tub with a capacity of 20 mL	03004058001
MPLC Reagent Tub (small)	150 tubs	MagNA Pure LC Reagent tub with a capacity of 3.5 mL	03004066001
MPLC Tub Lid (large)	120 lids	Lid for MPLC Reagent Tub (large) with tip access perforations	03004074001
MPLC Tub Lid (small, medium)	300 lids	Lid for MPLC Reagent Tub (Small, Medium) with tip access perforations	03004082001
MPLC Tub Lid Seal	400 seals	Seals for all MagNA Pure LC Tubs. Can be used as a liquid drop catcher	03004104001
MPLC Sample Cartridges	120 cartridges	32- well cartridge for starting samples, extraction elution and storage	03004112001
MPLC Processing Cartridges	160 cartridges	Cartridges used for extraction processing	03004147001
MPLC Tip Stand	200 tip stands	Tip storage during extraction run to minimize unnecessary tip use	03004155001
MPLC Reaction Tip (large)	960 tips	Tips for extraction. The pipeting volume range is 50 to 1000 µL	03004171001
MPLC Reaction Tip (small)	960 tips	Tips for extraction. The pipeting volume range is 5 to 50 µL	03004180001
MPLC Waste Bottle	40 bottles	Collects up to 330 mL of liquid waste	03004198001
MPLC Medium Reagent Tub 30	50 tubs	MagNA Pure LC Reagent Tub with a capacity of 30 mL	03045501001
MPLC Cartridge Seal	200 seals	Inert adhesive film used for sealing the MPLC Sample Cartridge for storage	03118827001
MPLC Barcode printer ribbon	1 ribbon	Printer ribbon for use on MagNA Pure LC Barcode Printer TLP 2844	03531538001
MagNA Pure LC 2.0 Waste Bags	25 bags	Waste Bags for MagNA Pure LC 2.0 Waste Box for the collection of used tip	05324157001

MagNA Pure LC 2.0 Accessories

Accessories for the MagNA Pure LC	Pack Size	Description	Product No.
MPLC Reagent Reservoir Rack	1 reagent rack	Additional rack for reagent tubs	03253767001
MPLC Reagent Tip Rack (Large Tips)	1 tip rack	MPLC Reagent Tip Rack (Large Tips) for replacement	03253775001
MPLC Reagent Tip Rack (Small Tips)	1 tip rack	MPLC Reagent Tip Rack (Small Tips) for replacement	03253783001
MPLC Liquid Waste Funnel	1 funnel	MPLC Liquid Waste Funnel for replacement	03253805001
MPLC Waste Bottle Tray	1 tray	MPLC Waste Bottle Tray for Replacement	03253813001
MPLC Greasing Set	1 set	MPLC Greasing Set for automated or manual greasing of the O-Rings	03561402001
MPLC O-Ring Maintenance Kit	1 set	Greasing vial and O-rings for replacement	03561429001

^{* All MagNA Pure LC2.0 Kits, Consumables and Accessories are for general laboratory use unless otherwise noted.}

MagNA Pure LC 2.0 Software

Download and Installation Instruction (25 KB PDF-File)

Protocols for Total Nucleic Acid Kit - High Performance, up to 200 µL sample volume (26 KB ZIP-File)

Protocols for Total Nucleic Acid Kit - High Performance, 500 µL sample volume (15 KB ZIP-File)

Protocols for Total Nucleic Acid Kit - High Performance, 1,000 µL sample volume (10 KB ZIP-File)

Note: If a software version earlier than v 1.1.24 is installed on your MagNA Pure LC Instrument, please contact Roche prior to installation of these protocols to get an update to v 1.1.24.

MagNA Pure Compact System

Benchtop extraction for up to 8 samples in ~30 minutes

With intuitive touchscreen guidance, barcode scanning of kits, and preloaded protocols, the MagNA Pure Compact System offers a simplified benchtop solution for your automated extraction needs.

For general laboratory use.

Learn More

MagNA Pure Compact Reagents
MagNA Pure Compact Consumables
MagNA Pure Compact Accessories
MagNA Pure Compact Software

MagNA Pure Compact Reagents

	# of isolations	Target	Starting Material									Product No.
	# of isolations	Target	Whole Blood	Blood Cells	Plasma	Cell Culture	Serum	Body Fluids	Fresh Frozen Tissue	Swab	Sputum	Product No.
MagNA Pure Compact NA Isolation Kit I	32	Genomic DNA, Bacterial DNA or Viral DNA/RNA	X	X	X	X	X	X		C	C	03730964001
MagNA Pure Compact NA Isolation Kit I- Large Volume	32	Genomic DNA, Bacterial DNA or Viral DNA/RNA	X	X	X	X	X					03730972001
MagNA Pure Compact RNA Isolation Kit	32	Total RNA	X	X	X				X			04802993001
MagNA Pure Bacteria Lysis Buffer	20 mL	Lysis Buffer										04659180001
X : Roche Supported Protocols
C : Roche Supported Protocols in combination with the MagNA Pure Bacteria Lysis Buffer and DNA_Bacteria purification protocol

MagNA Pure Compact Consumables

Consumables for the MagNA Pure Compact	Pack Size	Description	Product No.
MP Compact Tip Tray Kit	10 tip trays	Replacement accessory for Leakage Test	03753166001

MagNA Pure Compact Accessories

Accessories for the MagNA Pure Compact	Pack Size	Description	Product No.
MagNA Pure Compact Cartridge Rack	1 cartridge rack	Additional cartridge rack for use with the MagNA Pure Compact Instrument	03788237001
MagNA Pure Compact Drip Tray	1 drip tray	Additional drip tray for use with the MagNA Pure Compact Instrument	04347005001
MagNA Pure Compact Drop Catcher	1 drop catcher	Additional drop catcher for use with the MagNA Pure Compact Instrument	03788270001
MagNA Pure Compact Elution Tube Rack	1 tube rack	Additional elution tube rack for use with the MagNA Pure Compact Instrument	03788288001
MagNA Pure Compact Tube Rack	1 tube rack	Additional elution tube rack for use with the MagNA Pure Compact Instrument	03788296001
MagNA Pure Compact Waste Tank	1 waste tank	Additional waste tank for use with the MagNA Pure Compact Instrument	03788300001

* All MagNA Pure Compact Kits, Consumables and Accessories are for general laboratory use unless otherwise noted.

MagNA Pure Compact Software

The current software version for the MagNA Pure Compact is V1.1.2 which contains the latest protocols as of today. In case an update is required please contact your local service representative.

Click here for an updated version of the MagNA Pure Compact RNA Isolation Kit protocol for the isolation of RNA from 200 µL mammalian blood. Protocols for RNA Isolation Kit - Isolation of RNA from 200 µL mammalian blood (8 KB ZIP-File)

Nucleic Acid Purification Reagents

MagNA Pure 96 System
1-96 samples in one hour

MagNA Pure 24 System
1-24 samples in 70 min

High Pure Kits
Manual Extraction

MagNA Pure LC 2.0 System
1-32 samples in one hour

MagNA Pure Compact System
1-8 samples in one hour

MagNA Pure 96 Reagents
MagNA Pure 24 Reagents
MagNA Pure LC 2.0
MagNA Pure Compact
High Pure Kits

MagNA Pure 96 Reagents

	# of Isolations	Target	Starting Material										Product No.
	# of Isolations	Target	Whole Blood	Plasma	Cell Culture	Serum	Body Fluids	Fresh Frozen Tissue	FFPE Tissue	Swab	Stool	Sputum	Product No.
MagNA Pure 96 DNA and Viral Nucleic Acid Small Volume Kit	3x192 (200 µL)	Genomic DNA	X		X			X	X				06543588001
		Bacterial DNA	X	X	X	X	X			X	X	X
		Viral DNA/RNA	X	X	X	X	X			X	X	X
MagNA Pure 96 DNA and Viral Nucleic Acid Large Volume Kit	3x96 (0.5 mL) 3x48 (1 mL)	Cell-free NA		X									06374891001
		Genomic DNA	X		X			X
		Bacterial DNA	X	X	X	X	X			X	X	X
		Viral RNA/DNA	X	X	X	X	X			X	X	X
MagNA Pure 96 Cellular RNA Large Volume Kit *	3x96 or 3x48	Total RNA	X		X			X	X				05467535001
X : Roche Supported Protocols

Lysis Buffer	Pack Size	Description	Product No.
MagNA Pure cfNA Buffer set	upto 96 isolations	External lysis buffer to enable the isolation of cell-free nucleic acid (cfNA)	07794398001
MagNA Pure 96 External Lysis Buffer	100 mL	External lysis buffer for Whole Blood, Plasma and Serum samples	06374913001
MagNA Pure 96 Bacterial Lysis Buffer	20 mL	External lysis buffer for various sample types with bacterial and viral targets	06374921001
MagNA Pure 96 DNA Tissue Lysis Buffer	100 mL	External lysis buffer for Tissue samples (FFPE and Fresh Frozen)	06640702001
S.T.A.R. Buffer (Stool Transport and Recovery)†	100 mL	External lysis buffer for Whole Blood, Plasma and Serum samples	03335208001

MagNA Pure 24 Reagents

	# of Isolations	Target	Starting Material								Product No.
	# of Isolations	Target	Whole Blood	Plasma	Serum	Fresh Frozen Tissue	Urine	Stool	Others*	Cultured Cells	Product No.
MagNA Pure 24 Total NA Isolation Kit	96 small volume (200 µL)	Genomic DNA and bacterial, fungal or viral NA	X	X	X	X (up to 5 mg)	X	X	X	X (up to 10⁵ cultured cells)	07658036001
	72 large volume (500 µL, 1000 µL)	Genomic DNA and bacterial, fungal or viral NA	X	X	X		X	X	X	X (up to 10⁶ cultured cells)
	72 extra large volume (2000 µL, 4000 µL)	Human cell-free nucleic acid		X
X: Roche Supported Protocols
*Other human sample types include sputum, Bronchoalveolar lavage, Cerebrospinal Fluid, and Swab (nasopharyngeal, cervical).

** MagNA Pure 24 Total NA Isolation Kit is for in vitro diagnostic use.

Additional Reagents or Lysis Buffers	Pack Size	Description	Product No.
MagNA Pure 24 MGP Set	12 tubes	Additional magnetic glass particles for isolations of nucleic acids. Single use	07806461001
MagNA Pure cfNA Buffer Set	Up to 96 isolations	For the isolation of cell-free nucleic acids from plasma samples	07794398001
MagNA Pure LC Total Nucleic Acid Isolation Kit – Lysis/Binding Buffer Refill	100 mL	For external lysis protocols	03246779001
MagNA Pure Bacteria Lysis Buffer	20 mL	For the isolation of bacterial, fungal, and viral nucleic acids	04659180001
MagNA Pure DNA Tissue Lysis Buffer	100 mL	For the isolation of nucleic acids from fresh frozen tissue	04805160001
S.T.A.R. Buffer (Stool Transport and Recovery Buffer)	100 mL	For stabilization, transport and recovery of nucleic acids in stool samples	03335208001

Additional Reagents and Lysis Buffers are for general laboratory use unless otherwise noted.

MagNA Pure 24 MGP Set is for in vitro diagnostic use.

MagNA Pure LC 2.0 Reagents

	# of isolations	Target	Starting Material											Product No.
	# of isolations	Target	Whole Blood	Blood Cells	Plasma	Cell Culture	Serum	Body Fluids	Fresh Frozen Tissue	FFPE Tissue	Swab	Stool	Sputum	Product No.
MagNA Pure LC DNA Isolation Kit I (Blood, Blood Cell)	192	Genomic or Bacterial DNA	X	X		X								03003990001
MagNA Pure LC DNA Isolation Kit II (Tissue)	192								X	X				03186229001
MagNA Pure LC DNA Isolation Kit III (Bacteria, Fungi)	192					X		X			C	C	C	03264785001
MagNA Pure LC DNA Isolation Kit- Large Volume	288		X	X		X								03310515001
MagNA Pure LC Total NA Isolation Kit	192	Viral DNA/RNA	X		X		X							03038505001
MagNA Pure LC Total NA Isolation Kit- Large Volume	192				X		X							03264793001
MagNA Pure LC Total NA Isolation Kit- High Performance	288		X		X		X							05323738001
MagNA Pure LC RNA Isolation Kit III (Tissue)	192	Total RNA							X	X				03330591001
MagNA Pure LC RNA Isolation Kit- High Performance	192	Total RNA	X	X		X								03542394001
MagNA Pure Bacteria Lysis Buffer	20 mL	Lysis Buffer												04659180001
X : Roche Supported Protocols
C : Roche Supported Protocols in combination with the MagNA Pure Bacteria Lysis Buffer and DNA_Bacteria purification protocol

MagNA Pure Compact Reagents

	# of isolations	Target	Starting Material									Product No.
	# of isolations	Target	Whole Blood	Blood Cells	Plasma	Cell Culture	Serum	Body Fluids	Fresh Frozen Tissue	Swab	Sputum	Product No.
MagNA Pure Compact NA Isolation Kit I	32	Genomic DNA, Bacterial DNA or Viral DNA/RNA	X	X	X	X	X	X		C	C	03730964001
MagNA Pure Compact NA Isolation Kit I- Large Volume	32	Genomic DNA, Bacterial DNA or Viral DNA/RNA	X	X	X	X	X					03730972001
MagNA Pure Compact RNA Isolation Kit	32	Total RNA	X	X	X				X			04802993001
MagNA Pure Bacteria Lysis Buffer	20 mL	Lysis Buffer										04659180001
X : Roche Supported Protocols
C : Roche Supported Protocols in combination with the MagNA Pure Bacteria Lysis Buffer and DNA_Bacteria purification protocol

High Pure Kits

Flexible Nucleic Acid Isolation

Fast, flexible, and easy to use, High Pure Kits facilitate nucleic acid isolation from a variety of sample materials. This proven technology offers unparalleled flexibility while delivering the high-quality results you need for your desired application.

Go Pure

Reagent Selection Guide

Not sure which kit is best for you? With the new Roche Reagent Selection guide, you can easily find which reagents are right for your applications.

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Instructions for Use and MSDS

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MagNA Pure Systems and Nucleic Acid Purification Reagents

MagNA Pure 24 Product Video