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Clean or messy: What your workspace says about you
Is your workspace pristine and clean? Or do coworkers marvel at your collection of half-empty coffee cups and tsk-tsk at the mess you’ve made? As you’ve probably guessed, your workspace can tell a story about your personality.
by Roche Life Science | Career & Lifestyle
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Preventing Degradation in Nucleic Acid Samples
Research grants from the National Institutes of Health have become increasingly competitive in recent years, forcing more investigators to search outside the federal organization to obtain critical funds.
by Roche Life Science | Lab Life - DNA & RNA Purification
Category: Lab Life
Preventing Degradation in Nucleic Acid Samples
Millions of biological samples are stored each year for diagnostic, research, or forensic use. The quality and reliability of nucleic acid samples plays a significant role in the success of any test.
January 01, 2018 by Roche Life Science | Lab Life - DNA & RNA Purification
DNA methylation: Advances in methylomics and the importance of strandedness
The post-human-genome-sequencing era has seen exponential advances in large-scale genomic analyses that have paved the way for systematic evaluation of epigenetic modifications.
May 02, 2016 by Roche Life Science | Lab Life - Epigenetics
High throughput screening: A partnership for academics within the pharma industry
Large pharmaceutical companies pioneered high-throughput screening (HTS) for drug discovery in the early 1990s
April 21, 2016 by Roche Life Science | Lab Life - High Throughput
Temperature gradient vs. homogeneity: How can gradient PCR optimize your qPCR assay?
Optimization of qPCR conditions is essential for maximizing efficacy and reproducibility of your assay.
March 21, 2016 by Roche Life Science | Lab Life - Real-Time PCR
Genetic counselors and next-generation sequencing: The clinical implications of NGS patient data
As the wave of NGS clinical genetic applications and availability continues to rise, we must remain aware of the significant challenges to be addre
March 09, 2016 by Roche Life Science | Lab Life - Next-Gen Sequencing
Nucleic acid isolation for next-generation sequencing
In this article we will discuss the critical factors involved in the extraction of highly pure RNA or DNA from your experimental samples for NGS library preparation.
February 09, 2016 by Roche Life Science | Lab Life - Next-Gen Sequencing
Top 5 rookie qPCR mistakes and how to avoid them
Optimization of qPCR conditions is essential for maximizing efficacy and reproducibility of your assay.
January 12, 2016 by Roche Life Science | Lab Life - Real-Time PCR
What's template got to do with it?
In this article, we will discuss the importance of starting with a high-quality cDNA template for your RT-qPCR experiments and our top tips for how to do so.
December 01, 2015 by Roche Life Science | Lab Life - DNA & RNA Purification
Way to probe
We will summarize the most popular fluorescent probe-based real-time PCR chemistries.
November 02, 2015 by Roche Life Science | Lab Life - Real-Time PCR
Top 5 reasons your qPCR data was rejected: An insider perspective
In this article, we will discuss the top five reasons your qPCR data was rejected and how to combat these pitfalls
October 26, 2015 by Roche Life Science | Lab Life - Real-Time PCR
Important factors to consider for thermal shift assays
Multiple studies have sought to identify protein stabilizing drugs using thermal shift assays.
September 28, 2015 by Roche Life Science | Lab Life - High Throughput
At the dawn of methylation
In this article, we will discuss some of the basic principles of DNA methylation as well as highlight recent advances in our understanding of dynamic DNA methylation patterns.
September 25, 2015 by Roche Life Science | Lab Life - Epigenetics
Compare and Contrast: Multiplex vs. Singleplex PCR
Today, in the world of real-time PCR, there remain critical aspects of assay design that must be considered for optimization and to maximize cost- and time-efficiency.
September 19, 2015 by Roche Life Science | Lab Life - Real-Time PCR
It's all in the mix!
Is your PCR master mix optimized?
September 09, 2015 by Roche Life Science | Lab Life - Real-Time PCR
The top 10 things your post-doc will steal from you
After the honeymoon phase of finishing your dissertation, you begin to experience what many before you have bravely faced, what we like to unaffectionately refer to as "post-doc stress syndrome."
September 08, 2015 by Roche Life Science | Lab Life
5 must-dos when evaluating a PCR master mix reagent
When it comes to PCR, the success of your assay is dependent upon the quality and reliability of the reagents you use.
August 08, 2015 by Roche Life Science | Lab Life - Real-Time PCR
The top pros and cons of different RNA extraction methods
Making sure you are getting the most from your RNA isolation procedure is a must.
August 04, 2015 by Roche Life Science | Lab Life - DNA & RNA Purification
What is the fuel in your engine?
The instruments in your lab that you routinely depend upon for their consistent and reliable performance must be treated with the same thoughtful care for the fuel in their engines.
July 22, 2015 by Roche Life Science | Lab Life - Real-Time PCR
Next generation sequencing: Where are we now?
The last decade of advancements in genetic technologies has revolutionized massively parallel DNA sequencing (also known as next- or second-generation sequencing), opening the floodgates for unprecedented scientific inquiry and diagnostic capabilities.
June 29, 2015 by Roche Life Science | Lab Life - Next-Gen Sequencing
The evolution and future of gene expression
Over the past three decades, there have been tremendous advancements in the technical assays of gene expression.
June 26, 2015 by Roche Life Science | Lab Life - Next-Gen Sequencing
The lab decathlon: Are you up for the challenge?
Mastering the skills to succeed in the lab is not unlike those performed on the field.
June 23, 2015 by Roche Life Science | Lab Life
Kits vs. individual reagents
To kit or not to kit? Chances are, if you have not yet faced this dilemma, you soon will.
May 23, 2015 by Roche Life Science | Lab Life
What Apple and DNA-apps could mean for researchers
Apple is now collaborating with multiple U.S. academic research institutions to launch apps that would let iOS users have their DNA tested, according to a recent MIT Technology Review,
May 13, 2015 by Roche Life Science | Lab Life
Maximizing ROI with your nucleic acid extraction system
The extraction and purification of nucleic acids is no longer the complicated, labor-intensive process that it once was. See why.
by Roche Life Science | Lab Life - DNA & RNA Purification
The evolution of qPCR: Improving accuracy and reproducibility
It’s been more than three decades since polymerase chain reaction (PCR) technology revolutionized the lab and the process is continually evolving. See how.
by Roche Life Science | Lab Life - Real-Time PCR
Top 9 reasons why your assay isn’t working
Your PCR assay is one of the most common tools used in your lab. Yet for something you do day in, day out, there will always be those days where nothing seems to be going right.
by Roche Life Science | Lab Life - Real-Time PCR
Ensure reproducibility and repeatability with optimized master mixes
In the life sciences, it’s critical that researchers independently corroborate and validate others’ results. This means that the quality of a lab’s experimental results is only as good as another lab’s ability to reproduce the published findings.
by Roche Life Science | Lab Life - Real-Time PCR
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