Millions of biological samples are stored each year for diagnostic, research, or forensic use. The quality and reliability of nucleic acid samples plays a significant role in the success of any test.

January 01, 2018 by Roche Life Science | Lab Life - DNA & RNA Purification

The post-human-genome-sequencing era has seen exponential advances in large-scale genomic analyses that have paved the way for systematic evaluation of epigenetic modifications.

May 02, 2016 by Roche Life Science | Lab Life - Epigenetics

Large pharmaceutical companies pioneered high-throughput screening (HTS) for drug discovery in the early 1990s

April 21, 2016 by Roche Life Science | Lab Life - High Throughput

Optimization of qPCR conditions is essential for maximizing efficacy and reproducibility of your assay.

March 21, 2016 by Roche Life Science | Lab Life - Real-Time PCR

As the wave of NGS clinical genetic applications and availability continues to rise, we must remain aware of the significant challenges to be addre

March 09, 2016 by Roche Life Science | Lab Life - Next-Gen Sequencing

In this article we will discuss the critical factors involved in the extraction of highly pure RNA or DNA from your experimental samples for NGS library preparation.

February 09, 2016 by Roche Life Science | Lab Life - Next-Gen Sequencing

Optimization of qPCR conditions is essential for maximizing efficacy and reproducibility of your assay.

January 12, 2016 by Roche Life Science | Lab Life - Real-Time PCR

In this article, we will discuss the importance of starting with a high-quality cDNA template for your RT-qPCR experiments and our top tips for how to do so.

December 01, 2015 by Roche Life Science | Lab Life - DNA & RNA Purification

We will summarize the most popular fluorescent probe-based real-time PCR chemistries.

November 02, 2015 by Roche Life Science | Lab Life - Real-Time PCR

In this article, we will discuss the top five reasons your qPCR data was rejected and how to combat these pitfalls

October 26, 2015 by Roche Life Science | Lab Life - Real-Time PCR

Multiple studies have sought to identify protein stabilizing drugs using thermal shift assays.

September 28, 2015 by Roche Life Science | Lab Life - High Throughput

In this article, we will discuss some of the basic principles of DNA methylation as well as highlight recent advances in our understanding of dynamic DNA methylation patterns.

September 25, 2015 by Roche Life Science | Lab Life - Epigenetics

Today, in the world of real-time PCR, there remain critical aspects of assay design that must be considered for optimization and to maximize cost- and time-efficiency.

September 19, 2015 by Roche Life Science | Lab Life - Real-Time PCR

Is your PCR master mix optimized?

September 09, 2015 by Roche Life Science | Lab Life - Real-Time PCR

After the honeymoon phase of finishing your dissertation, you begin to experience what many before you have bravely faced, what we like to unaffectionately refer to as "post-doc stress syndrome."

September 08, 2015 by Roche Life Science | Lab Life

When it comes to PCR, the success of your assay is dependent upon the quality and reliability of the reagents you use.

August 08, 2015 by Roche Life Science | Lab Life - Real-Time PCR

Making sure you are getting the most from your RNA isolation procedure is a must.

August 04, 2015 by Roche Life Science | Lab Life - DNA & RNA Purification

The instruments in your lab that you routinely depend upon for their consistent and reliable performance must be treated with the same thoughtful care for the fuel in their engines.

July 22, 2015 by Roche Life Science | Lab Life - Real-Time PCR

The last decade of advancements in genetic technologies has revolutionized massively parallel DNA sequencing (also known as next- or second-generation sequencing), opening the floodgates for unprecedented scientific inquiry and diagnostic capabilities.

June 29, 2015 by Roche Life Science | Lab Life - Next-Gen Sequencing

Over the past three decades, there have been tremendous advancements in the technical assays of gene expression.

June 26, 2015 by Roche Life Science | Lab Life - Next-Gen Sequencing

Mastering the skills to succeed in the lab is not unlike those performed on the field.

June 23, 2015 by Roche Life Science | Lab Life

To kit or not to kit? Chances are, if you have not yet faced this dilemma, you soon will.

May 23, 2015 by Roche Life Science | Lab Life

Apple is now collaborating with multiple U.S. academic research institutions to launch apps that would let iOS users have their DNA tested, according to a recent MIT Technology Review,

May 13, 2015 by Roche Life Science | Lab Life

The extraction and purification of nucleic acids is no longer the complicated, labor-intensive process that it once was. See why.

by Roche Life Science | Lab Life - DNA & RNA Purification

It’s been more than three decades since polymerase chain reaction (PCR) technology revolutionized the lab and the process is continually evolving. See how.

by Roche Life Science | Lab Life - Real-Time PCR

Your PCR assay is one of the most common tools used in your lab. Yet for something you do day in, day out, there will always be those days where nothing seems to be going right.

by Roche Life Science | Lab Life - Real-Time PCR

In the life sciences, it’s critical that researchers independently corroborate and validate others’ results. This means that the quality of a lab’s experimental results is only as good as another lab’s ability to reproduce the published findings.

by Roche Life Science | Lab Life - Real-Time PCR