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MagNA Pure 24 Total NA Isolation Kit

Universal reagent kit in pre-filled and ready-to-use cassettes for isolating nucleic acids using the MagNA Pure 24 Instrument.
For in vitro diagnostic use.

Product No. Pack Size
07658036001 up to 96 extractions

To order these products, please contact your Roche order management team.

The MagNA Pure 24 Total Nucleic Acid Kit eliminates unnecessary complexity by enabling efficient extraction of nucleic acids from 10 human sample types. Rely on this simplified reagent concept and choose one of the pre-optimized and pre-programmed protocols to extract up to 24 samples in just over an hour, plus:

  • Mix batch sample types and primary tubes within one protocol
  • Run sample volume inputs ranging from 200 µL to 4 mL
  • Reuse reagent cassettes for later use by sealing them
  • Let the system identify and track reagent usage with on-board barcode scanning
  • Expand your applications with a multitude of compatible external lysis buffers
  • Extract 8 samples in less than 30 minutes with the fast protocol

MagNA Pure 24 Total NA Isolation Kit contains prefilled and ready-to-use reagent cassettes, that can be easily loaded into their stations, and single use magnetic glass particles (MGPs) vials, that can be easily loaded into the reagent racks. Additional MGPs and external lysis buffers can be ordered separately to enhance your extraction workflow. A variety of targets from a wide range of sample types can be extracted efficiently on the MagNA Pure 24 System using one kit and one protocol in the same run. The different protocols are optimized for the following human sample materials:

  • Whole Blood
  • Plasma
  • Serum
  • Bronchoalveolar lavage
  • Swab
  • Urine
  • Stool
  • Fresh/Frozen Tissue


Each kit is comprised of 3 sealed reagent cassettes and 12 magnetic glass particle (MGP) tubes. All kit components are ready-to-use. One reagent cassette can be used for up to 6 individual runs on the same instrument within 28 days. For storage after first use, seal the reagent cassettes using the MagNA Pure Sealing Foil.

MGP tubes are for single use only.

The MagNA Pure 24 Total NA Isolation Kit is designed to isolate nucleic acids (NA) from different sample materials and different sample volumes as shown in the following table:

Target material

Sample material

Genomic DNA


  • 200, 500 or 1000 µL whole blood
  • up to 1 x 106 of cultured cells
  • up to 5 mg of fresh-frozen tissue

Bacterial, fungal or viral NA


  • 200, 500 or 1000 µL of plasma, serum, whole blood and other materials of human origin

Human cell-free NA


  • 2000 or 4000 µL of plasma

The isolated and purified nucleic acids meet the quality standards required for highly sensitive quantitative PCR/RT-PCR analysis and next-generation sequencing.

The kit is designed to perform up to 96 isolations depending on the processed sample volume. Each kit has 3 cassettes and each cassette can perform 32 small or 24 large/extra-large volume isolations.

Number of isolations (per kit)

Sample material

3 x 32 isolations


Small volume:

Up to 200 µL plasma, serum, whole blood, and other materials of human origin, up to 5 x 105 cultured cells, and up to 5 mg of fresh-frozen tissue.

3 x 24 isolations


Large volume:

500 µL or 1000 µL of plasma, serum, whole blood, and other materials of human origin, up to 1 x 10cultured cells.

3 x 24 isolations


Extra-large volume:

2000 µL or 4000 µL of plasma.

To process extra-large sample volumes, the MagNA Pure cfNA Buffer Set is required.


Additional MagNA Pure 24 reagents:



Catalog number

MagNA Pure 24 MGP Set

For additional isolations of nucleic acids from small, large, and extra-large sample volumes.

07 806 361 001

MagNA Pure cfNA Buffer Set

For the isolation of cell-free nucleic acids from plasma samples.

07 794 398 001

MagNA Pure LC Total Nucleic Acid Isolation Kit – Lysis/Binding Buffer Refill

For external lysis protocols.

03 246 779 001

MagNA Pure Bacteria Lysis Buffer

For the isolation of bacterial, fungal, and viral nucleic acids.

04 659 180 001

MagNA Pure DNA Tissue Lysis Buffer

For the isolation of nucleic acids from fresh-frozen tissue.

04 805 160 001

S.T.A.R. buffer

(Stool Transport and Recovery Buffer)

For stabilization, transport, and recovery of nucleic acids in stool samples.

03 335 208 001