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Mouse Anti-Human c-erbB-3/HER-3 Monoclonal Antibody (Clone SPM738)

For research use only. Not for use in diagnostics.

Product No. Pack Size
07787073001 0.1 mL
Product No. Pack Size
07787090001 1.0 mL

To order these products, please contact your Roche order management team.

Receptor tyrosine-protein kinase erbB-3 or c-erbB-3, also known as HER3 (human epidermal growth factor receptor 3), a member of the epidermal growth factor receptor (EGFR/ERBB) family of receptor tyrosine kinases. It is expressed in normal adult human gastrointestinal tract, nervous system, urinary tract, reproductive system, skin, and endocrine system. The c-erbB-3 is overexpressed in a variety of tumors from head and neck, breast, stomach, pancreas, and colon.

Figure above:
Human small intestine stained with anti-c-erbB-3 (cloneSPM738) antibody

Contents

Mouse monoclonal antibody purified by protein A/G in Tris buffer pH 7.5 with 0.3% carrier protein and less than 0.1% sodium azide.

IHC Performance

 

Human small intestine stained with anti-c-erbB-3 (cloneSPM738) antibody
Human small intestine stained with anti-c-erbB-3 (cloneSPM738) antibody

Product Details:

 

Technology

Mouse Monoclonal

Clone Name

SPM738

Application

IHC

Species Reactivity

 

   Tested

Hu

   Predicted by homology

Ms, Rt

Isotype

Mouse IgG2a/k

Immunogen

Synthetic peptide near the C-terminus of human c-erbB-3 protein.

Cellular Localization

Membrane

Control Tissue

Small Intestine

Regulatory Rating

Research Use Only (RUO)

Entrez

2065

Storage Requirement

2-8°C

Target Molecular Weight

148 kDa

Formulation

Refer to Data Sheet