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Rabbit Anti-CDX2 Monoclonal Antibody (Clone SP54)

For research use only. Not for use in diagnostics.

Product No. Pack Size
06970940001 0.1 mL
Product No. Pack Size
06970974001 1.0 mL

To order these products, please contact your Roche order management team.

CDX2 is a caudal type homeobox gene that encodes an intenstine-specific transcription factor that is expressed early in intestinal development and may be involved in the regulation of proliferation and differentiation of intestinal epithelial cells. It is expressed in the nuclei of epithelial cells throughout the intestine, from duodenum to rectum. The CDX2 protein is expressed in primary and metastatic colorectal carcinomas and has also been demonstrated in the intestinal metaplasia of the stomach and intestinal-type gastric cancer, while it is not expressed in the normal gastric mucosa. Studies have shown that CDX2 is superior marker compared in CK20.

Figure above:
Human Colon Carcinoma stained with anti-CDX2 antibody

Contents

Rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.

IHC Performance

 

Human Colon Carcinoma stained with anti-CDX2 antibody

Human Colon Carcinoma stained with anti-CDX2 antibody



Flow Cytometric Analysis

 

Flow cytometric analysis of rabbit anti-CDX2 (SP54) antibody in HT29 (green) compare to negative control of rabbit IgG (blue)
Flow cytometric analysis of rabbit anti-CDX2 (SP54) antibody in HT29 (green) compare to negative control of rabbit IgG (blue)


Product Details:

 

Technology

Rabbit Monoclonal

Clone Name

SP54

Application

IHC-P, FACS

Species Reactivity

 

Tested

Hu

Predicted by homology

Hm, Ms

Isotype

Rabbit IgG

Immunogen

Synthetic peptide corresponding to N-terminus of human CDX2.

Cellular Localization

Nucleus

Control Tissue

Colon Carcinoma

Regulatory Rating

Research Use Only (RUO)

Entrez

1045

Storage Requirement

2-8°C

Target Molecular Weight

37 kDa

Formulation

Refer to Data Sheet