Rabbit Anti-Human Androgen Receptor (AR) (C-term) Monoclonal Antibody (Clone SP242)
For research use only. Not for use in diagnostics.
| Product No. | Pack Size |
|---|---|
| 07154127001 | 0.1 mL |
| Product No. | Pack Size |
|---|---|
| 07154143001 | 1.0 mL |
To order these products, please contact your Roche order management team.
Androgen receptor (AR) is a receptor for the androgenic hormones testosterone or dihydrotestosterone and it is a member of the steroid superfamily of ligand-dependent transcription factors. In the absence of androgen, the unligated AR mainly locates in cytoplasm, but translocates to the nucleus upon binding to androgen. Truncated AR variants with loss of C-terminus are common in prostate cancer. **Please contact us for availability**
Figure above:
Human prostate adenocarcinoma stained with anti-AR (C-term) antibody
Contents
Rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.
IHC Performance
|
Human prostate adenocarcinoma stained with anti-AR (C-term) antibody |
Product Details:
Technology |
Rabbit Monoclonal |
Clone Name |
SP242 |
Application |
IHC-P |
Species Reactivity |
|
Tested |
Hu |
Predicted by homology |
Dg, Ms, Pg, Rb, Rt |
Isotype |
Rabbit IgG |
Immunogen |
Synthetic peptide from the C-terminus of human androgen receptor protein. |
Cellular Localization |
Cytoplasm, Nucleus |
Control Tissue |
Prostate, Prostate Adenocarcinoma |
Regulatory Rating |
Research Use Only (RUO) |
Entrez |
367 |
Storage Requirement |
2-8°C |
Target Molecular Weight |
110 kDa |
Formulation |
Refer to Data Sheet |
Instructions for Use (IFU)
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