Rabbit Anti-Human Androgen Receptor (AR) (C-term) Monoclonal Antibody (Clone SP242)

For research use only. Not for use in diagnostics.

Product No. Pack Size
07154127001 0.1 mL
Product No. Pack Size
07154143001 1.0 mL

To order these products, please contact your Roche order management team.

Androgen receptor (AR) is a receptor for the androgenic hormones testosterone or dihydrotestosterone and it is a member of the steroid superfamily of ligand-dependent transcription factors. In the absence of androgen, the unligated AR mainly locates in cytoplasm, but translocates to the nucleus upon binding to androgen. Truncated AR variants with loss of C-terminus are common in prostate cancer. **Please contact us for availability**

Figure above:
Human prostate adenocarcinoma stained with anti-AR (C-term) antibody

Contents

Rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.

IHC Performance

 

Human Prostate adenocarcinoma stained with anti-AR (C-term) antibody

Human prostate adenocarcinoma stained with anti-AR (C-term) antibody

Product Details:

 

Technology

Rabbit Monoclonal

Clone Name

SP242

Application

IHC-P

Species Reactivity

 

   Tested

Hu

   Predicted by homology

Dg, Ms, Pg, Rb, Rt

Isotype

Rabbit IgG

Immunogen

Synthetic peptide from the C-terminus of human androgen receptor protein.

Cellular Localization

Cytoplasm, Nucleus

Control Tissue

Prostate, Prostate Adenocarcinoma

Regulatory Rating

Research Use Only (RUO)

Entrez

367

Storage Requirement

2-8°C

Target Molecular Weight

110 kDa

Formulation

Refer to Data Sheet