Rabbit Anti-Human Androgen Receptor (AR) (C-term) Monoclonal Antibody (Clone SP242)

Androgen receptor (AR) is a receptor for the androgenic hormones testosterone or dihydrotestosterone and it is a member of the steroid superfamily of ligand-dependent transcription factors. In the absence of androgen, the unligated AR mainly locates in cytoplasm, but translocates to the nucleus upon binding to androgen. Truncated AR variants with loss of C-terminus are common in prostate cancer. **Please contact us for availability**

Figure above:
Human prostate adenocarcinoma stained with anti-AR (C-term) antibody

Contents

Rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.