Rabbit Anti-Human BCL-6 Monoclonal Antibody (Clone SP155)

For research use only. Not for use in diagnostics.

Product No.	Pack Size
06974767001	0.1 mL

Product No.	Pack Size
06974791001	1.0 mL

To order these products, please contact your Roche order management team.

Keywords: Antibodies, Rabbit Monoclonal

B cell lymphoma 6 protein (Bcl-6) proto-oncogene product (a Kruppel-type zinc-finger protein) is mainly expressed in normal germinal center B cells and related lymphomas. Bcl-6 is involved in chromosome rearrangements at 3q27 in non-Hodgkin’s lymphomas and Bcl-6 rearrangements have been detected in 33%-45% of diffuse large B cell lymphomas. Bcl-6 has been detected immunohistochemically in follicular lymphomas, diffuse large B cell lymphomas, Burkitt lymphomas and in nodular, lymphocyte predominant Hodgkin’s disease.

Figure above:
Human tonsil stained with anti-BCL-6 antibody

Contents

Rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.

IHC Performance


Human tonsil stained with anti-BCL-6 antibody	Human B-Cell Lymphoma stained with anti-BCL-6 antibody	Human Tonsil stained with anti-BCL-6 antibody	Human B-Cell Lymphoma stained with anti-BCL-6 antibody

Human HK Lymphoma stained with anti-BCL-6 antibody	Human Follicular Lymphoma stained with anti-BCL-6 antibody	Human Diffuse B-Cell Lymphoma stained with anti-BCL-6 antibody

Flow Cytometric Analysis

Flow cytometric analysis of rabbit anti-BCL-6 (SP155) antibody in RAMOS (green) compare to negative control of rabbit IgG (blue)

Product Details:

Technology	Rabbit Monoclonal
Clone Name	SP155
Application	IHC-P, FACS
Species Reactivity
Tested	Hu
Predicted by homology	Ms, Rt
Isotype	Rabbit IgG
Immunogen	Synthetic peptide derived from the C-terminus of human BCL-6 protein.
Cellular Localization	Nucleus
Control Tissue	Tonsil
Regulatory Rating	Research Use Only (RUO)
Entrez	604
Storage Requirement	2-8°C
Target Molecular Weight	78 kDa
Formulation	Refer to Data Sheet

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