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Rabbit Anti-Human BCL-6 Monoclonal Antibody (Clone SP155)

For research use only. Not for use in diagnostics.

Product No. Pack Size
06974767001 0.1 mL
Product No. Pack Size
06974791001 1.0 mL

To order these products, please contact your Roche order management team.

B cell lymphoma 6 protein (Bcl-6) proto-oncogene product (a Kruppel-type zinc-finger protein) is mainly expressed in normal germinal center B cells and related lymphomas. Bcl-6 is involved in chromosome rearrangements at 3q27 in non-Hodgkin’s lymphomas and Bcl-6 rearrangements have been detected in 33%-45% of diffuse large B cell lymphomas. Bcl-6 has been detected immunohistochemically in follicular lymphomas, diffuse large B cell lymphomas, Burkitt lymphomas and in nodular, lymphocyte predominant Hodgkin’s disease.

Figure above:
Human tonsil stained with anti-BCL-6 antibody

Contents

Rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.

IHC Performance

 

Human tonsil stained with anti-BCL-6 antibody

Human B-Cell Lymphoma stained with anti-BCL-6 antibody

Human Tonsil stained with anti-BCL-6 antibody

Human B-Cell Lymphoma stained with anti-BCL-6 antibody

Human tonsil stained with anti-BCL-6 antibody

Human B-Cell Lymphoma stained with anti-BCL-6 antibody

Human Tonsil stained with anti-BCL-6 antibody

Human B-Cell Lymphoma stained with anti-BCL-6 antibody

Human HK Lymphoma stained with anti-BCL-6 antibody

Human Follicular Lymphoma stained with anti-BCL-6 antibody

Human Diffuse B-Cell Lymphoma stained with anti-BCL-6 antibody

Human HK Lymphoma stained with anti-BCL-6 antibody

Human Follicular Lymphoma stained with anti-BCL-6 antibody

Human Diffuse B-Cell Lymphoma stained with anti-BCL-6 antibody

 

Flow Cytometric Analysis

 

Flow cytometric analysis of rabbit anti-BCL-6 (SP155) antibody in RAMOS (green) compare to negative control of rabbit IgG (blue)
Flow cytometric analysis of rabbit anti-BCL-6 (SP155) antibody in RAMOS (green) compare to negative control of rabbit IgG (blue)


Product Details:

 

Technology

Rabbit Monoclonal

Clone Name

SP155

Application

IHC-P, FACS

Species Reactivity

 

   Tested

Hu

   Predicted by homology

Ms, Rt

Isotype

Rabbit IgG

Immunogen

Synthetic peptide derived from the C-terminus of human BCL-6 protein.

Cellular Localization

Nucleus

Control Tissue

Tonsil

Regulatory Rating

Research Use Only (RUO)

Entrez

604

Storage Requirement

2-8°C

Target Molecular Weight

78 kDa

Formulation

Refer to Data Sheet