Rabbit Anti-Human BCL-6 Monoclonal Antibody (Clone SP155)
For research use only. Not for use in diagnostics.
Product No. | Pack Size |
---|---|
06974767001 | 0.1 mL |
Product No. | Pack Size |
---|---|
06974791001 | 1.0 mL |
To order these products, please contact your Roche order management team.
B cell lymphoma 6 protein (Bcl-6) proto-oncogene product (a Kruppel-type zinc-finger protein) is mainly expressed in normal germinal center B cells and related lymphomas. Bcl-6 is involved in chromosome rearrangements at 3q27 in non-Hodgkin’s lymphomas and Bcl-6 rearrangements have been detected in 33%-45% of diffuse large B cell lymphomas. Bcl-6 has been detected immunohistochemically in follicular lymphomas, diffuse large B cell lymphomas, Burkitt lymphomas and in nodular, lymphocyte predominant Hodgkin’s disease.
Figure above:
Human tonsil stained with anti-BCL-6 antibody
Contents
Rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.
IHC Performance
Human tonsil stained with anti-BCL-6 antibody |
Human B-Cell Lymphoma stained with anti-BCL-6 antibody |
Human Tonsil stained with anti-BCL-6 antibody |
Human B-Cell Lymphoma stained with anti-BCL-6 antibody |
Human HK Lymphoma stained with anti-BCL-6 antibody |
Human Follicular Lymphoma stained with anti-BCL-6 antibody |
Human Diffuse B-Cell Lymphoma stained with anti-BCL-6 antibody |
Flow Cytometric Analysis
Flow cytometric analysis of rabbit anti-BCL-6 (SP155) antibody in RAMOS (green) compare to negative control of rabbit IgG (blue)
Product Details:
Technology |
Rabbit Monoclonal |
Clone Name |
SP155 |
Application |
IHC-P, FACS |
Species Reactivity |
|
Tested |
Hu |
Predicted by homology |
Ms, Rt |
Isotype |
Rabbit IgG |
Immunogen |
Synthetic peptide derived from the C-terminus of human BCL-6 protein. |
Cellular Localization |
Nucleus |
Control Tissue |
Tonsil |
Regulatory Rating |
Research Use Only (RUO) |
Entrez |
604 |
Storage Requirement |
2-8°C |
Target Molecular Weight |
78 kDa |
Formulation |
Refer to Data Sheet |