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Rabbit Anti-Human CD163 Monoclonal Antibody (Clone SP96)

For research use only. Not for use in diagnostics.

Product No. Pack Size
06972624001 0.1 mL
Product No. Pack Size
06972616001 1.0 mL

To order these products, please contact your Roche order management team.

CD163 is a 130kDa membrane glycoprotein. It is a member of the scavenger receptor cysteine-rich superfamily and is a receptor for the hemoglobin-haptoglobin complex. CD163 is expressed exclusively on the cell surface of human monocytes and macrophages that evolve predominantly in the late phase of inflammation. CD163 is present on all CD14 positive monocytes, most CD64 positive monocytes, and shows higher expression on CD16 positive monocytes. CD163 is upregulated on mononuclear phagocytes by IL-10, IL-6 and dexamethasone. Lipopolysaccharide (LPS) and phorbol myristate acetate (PMA) both induce shedding of CD163 from the cell surface into plasma or cell supernatant.

Figure above:
Human Lung stained with anti-CD163 antibody

Contents

Rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.

IHC Performance

 

Human Lung stained with anti-CD163 antibody

Human Bone Marrow stained with anti-CD163 antibody

Human Esophagus stained with anti-CD163 antibody

Human Ovary stained with anti-CD163 antibody

Human Lung stained with anti-CD163 antibody

Human Bone Marrow stained with anti-CD163 antibody

Human Esophagus stained with anti-CD163 antibody

Human Ovary stained with anti-CD163 antibody

Human Reactive Lymph Node stained with anti-CD163 antibody

Human Thymus stained with anti-CD163 antibody

Human Tonsil stained with anti-CD163 antibody

Human Reactive Lymph Node stained with anti-CD163 antibody

Human Thymus stained with anti-CD163 antibody

Human Tonsil stained with anti-CD163 antibody

Product Details:

Technology

Rabbit Monoclonal

Clone Name

SP96

Application

IHC-P

Species Reactivity

 

   Tested

Hu

   Predicted by homology

Bv, Pg

Isotype

Rabbit IgG

Immunogen

Synthetic peptide corresponding to near N-terminus of human CD163 protein.

Cellular Localization

Membrane

Control Tissue

Lung

Regulatory Rating

Research Use Only (RUO)

Entrez

9332

Storage Requirement

2-8°C

Target Molecular Weight

130 kDa

Formulation

Refer to Data Sheet