Rabbit Anti-Human CD169 Monoclonal Antibody (Clone SP216)
For research use only. Not for use in diagnostics.
| Product No. | Pack Size |
|---|---|
| 07074298001 | 0.1 mL |
| Product No. | Pack Size |
|---|---|
| 07074310001 | 1.0 mL |
To order these products, please contact your Roche order management team.
CD169 or sialoadhesin is a cell adhesion molecule on the surface of some macrophages distributed in the spleen, liver, lymph node, bone marrow, colon, lung, and various inflammatory tissues. It acts as an endocytic receptor mediating clathrin-dependent endocytosis. CD169 predominately binds to neutrophils, but can also bind to monocytes, natural killer cells, B cells and a subset of cytotoxic T cells by interacting with sialic acid molecules on their surfaces of their ligands.
Figure above:
Human lymph node stained with anti-CD169 antibody
Contents
Rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.
IHC Performance
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Human Bone Marrow stained with anti-CD169 antibody |
Human Cervical Squamous Cell Carcinoma stained with anti-CD169 antibody |
Human HK Lymphoma stained with anti-CD169 antibody |
Human Lung Squamous Cell Carcinoma stained with anti-CD169 antibody |
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Human Lung stained with anti-CD169 antibody |
Human Lymph node stained with anti-CD169 antibody |
Product Details:
Technology |
Rabbit Monoclonal |
Clone Name |
SP216 |
Application |
IHC-P |
Species Reactivity |
|
Tested |
Hu |
Predicted by homology |
N/A |
Isotype |
Rabbit IgG |
Immunogen |
Synthetic peptide derived from the internal region of human CD169 protein. |
Cellular Localization |
Membrane |
Control Tissue |
Liver, Lung, Lymph Node |
Regulatory Rating |
Research Use Only (RUO) |
Entrez |
6614 |
Storage Requirement |
2-8°C |
Target Molecular Weight |
182 kDa |
Formulation |
Refer to Data Sheet |
Associated Products
Instructions for Use (IFU)
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