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Rabbit Anti-Human CD278 Monoclonal Antibody (Clone SP98 )

For research use only. Not for use in diagnostics.

Product No. Pack Size
06972691001 0.1 mL
Product No. Pack Size
06972721001 1.0 mL

To order these products, please contact your Roche order management team.

CD278 belongs to the CD28 and CTLA-4 cell-surface receptor family and is highly expressed in activated T-cells. It is essential both for efficient interaction between T and B-cells and for normal antibody responses to T-cell dependent antigens. It enhances all basic T-cell responses to a foreign antigen, namely proliferation, secretion of lymphokines, up-regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B-cells.

Figure above:
Human Reactive Lymph Node stained with anti-CD278/ICOS antibody

Contents

Rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.

IHC Performance

 

Human Reactive Lymph Node stained with anti-CD278/ICOS antibody

Human Cervical Squamous Cell Carcinoma stained with anti-CD278/ICOS antibody

Human Endometrium stained with anti-CD278/ICOS antibody

Human HK Lymphoma stained with anti-CD278/ICOS antibody

Human Lung Adenocarcinoma stained with anti-CD278/ICOS antibody

Human Lung Squamous Cell Carcinoma stained with anti-CD278/ICOS antibody

Human Pancreatic Adenocarcinoma stained with anti-CD278/ICOS antibody

Human Thymus stained with anti-CD278/ICOS antibody

Human Thyroid stained with anti-CD278/ICOS antibody

Human Tonsil stained with anti-CD278/ICOS antibody

Product Details:

 

Technology

Rabbit Monoclonal

Clone Name

SP98

Application

IHC-P

Species Reactivity

 

   Tested

Hu

   Predicted by homology

Rt

Isotype

Rabbit IgG

Immunogen

Synthetic peptide corresponding to C-terminus of human CD278.

Cellular Localization

Membrane

Control Tissue

Reactive Lymph Node, Tonsil

Regulatory Rating

Research Use Only (RUO)

Entrez

29851

Storage Requirement

2-8°C

Target Molecular Weight

23 kDa

Formulation

Refer to Data Sheet