Rabbit Anti-Human CD278 Monoclonal Antibody (Clone SP98 )
For research use only. Not for use in diagnostics.
Product No. | Pack Size |
---|---|
06972691001 | 0.1 mL |
Product No. | Pack Size |
---|---|
06972721001 | 1.0 mL |
To order these products, please contact your Roche order management team.
CD278 belongs to the CD28 and CTLA-4 cell-surface receptor family and is highly expressed in activated T-cells. It is essential both for efficient interaction between T and B-cells and for normal antibody responses to T-cell dependent antigens. It enhances all basic T-cell responses to a foreign antigen, namely proliferation, secretion of lymphokines, up-regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B-cells.
Figure above:
Human Reactive Lymph Node stained with anti-CD278/ICOS antibody
Contents
Rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.
IHC Performance
Human Reactive Lymph Node stained with anti-CD278/ICOS antibody |
Human Cervical Squamous Cell Carcinoma stained with anti-CD278/ICOS antibody |
Human Endometrium stained with anti-CD278/ICOS antibody |
Human HK Lymphoma stained with anti-CD278/ICOS antibody |
Human Lung Adenocarcinoma stained with anti-CD278/ICOS antibody |
Human Lung Squamous Cell Carcinoma stained with anti-CD278/ICOS antibody |
Human Pancreatic Adenocarcinoma stained with anti-CD278/ICOS antibody |
Human Thymus stained with anti-CD278/ICOS antibody |
Human Thyroid stained with anti-CD278/ICOS antibody |
Human Tonsil stained with anti-CD278/ICOS antibody |
Product Details:
Technology |
Rabbit Monoclonal |
Clone Name |
SP98 |
Application |
IHC-P |
Species Reactivity |
|
Tested |
Hu |
Predicted by homology |
Rt |
Isotype |
Rabbit IgG |
Immunogen |
Synthetic peptide corresponding to C-terminus of human CD278. |
Cellular Localization |
Membrane |
Control Tissue |
Reactive Lymph Node, Tonsil |
Regulatory Rating |
Research Use Only (RUO) |
Entrez |
29851 |
Storage Requirement |
2-8°C |
Target Molecular Weight |
23 kDa |
Formulation |
Refer to Data Sheet |