Rabbit Anti-Human CD278 Monoclonal Antibody (Clone SP98 )

For research use only. Not for use in diagnostics.

Product No.	Pack Size
06972691001	0.1 mL

Product No.	Pack Size
06972721001	1.0 mL

To order these products, please contact your Roche order management team.

Keywords: Antibodies, Rabbit Monoclonal

CD278 belongs to the CD28 and CTLA-4 cell-surface receptor family and is highly expressed in activated T-cells. It is essential both for efficient interaction between T and B-cells and for normal antibody responses to T-cell dependent antigens. It enhances all basic T-cell responses to a foreign antigen, namely proliferation, secretion of lymphokines, up-regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B-cells.

Figure above:
Human Reactive Lymph Node stained with anti-CD278/ICOS antibody

Contents

Rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.

IHC Performance


Human Reactive Lymph Node stained with anti-CD278/ICOS antibody	Human Cervical Squamous Cell Carcinoma stained with anti-CD278/ICOS antibody	Human Endometrium stained with anti-CD278/ICOS antibody	Human HK Lymphoma stained with anti-CD278/ICOS antibody

Human Lung Adenocarcinoma stained with anti-CD278/ICOS antibody	Human Lung Squamous Cell Carcinoma stained with anti-CD278/ICOS antibody	Human Pancreatic Adenocarcinoma stained with anti-CD278/ICOS antibody	Human Thymus stained with anti-CD278/ICOS antibody

Human Thyroid stained with anti-CD278/ICOS antibody	Human Tonsil stained with anti-CD278/ICOS antibody

Product Details:

Technology	Rabbit Monoclonal
Clone Name	SP98
Application	IHC-P
Species Reactivity
Tested	Hu
Predicted by homology	Rt
Isotype	Rabbit IgG
Immunogen	Synthetic peptide corresponding to C-terminus of human CD278.
Cellular Localization	Membrane
Control Tissue	Reactive Lymph Node, Tonsil
Regulatory Rating	Research Use Only (RUO)
Entrez	29851
Storage Requirement	2-8°C
Target Molecular Weight	23 kDa
Formulation	Refer to Data Sheet

Associated Products

Rabbit Anti-Human B7-H3/CD276 Monoclonal Antibody (Clone SP206) Read more

Rabbit Anti-Human FoxP3 Monoclonal Antibody (Clone SP97) Read more

Rabbit Anti-Human IDO-1 Monoclonal Antibody (Clone SP260) Read more

Rabbit Anti-Human OX40 Monoclonal Antibody (Clone SP195) Read more

Rabbit Anti-Human PD-1/CD279 Monoclonal Antibody (Clone SP269) Read more

Rabbit Anti-Human PD-L1/CD274 Monoclonal Antibody (Clone SP142) Read more

Products are for life science research only. Not for use in diagnostic procedures unless otherwise indicated. This website contains information on products which is targeted to a wide range of audiences and could contain product details or information otherwise not accessible or valid in your country. Please be aware that we do not take any responsibility for accessing such information which may not comply with any valid legal process, regulation, registration or usage in the country of your origin.