Rabbit Anti-Human CD35 Monoclonal Antibody (Clone SP197)
For research use only. Not for use in diagnostics.
Product No. | Pack Size |
---|---|
06914071001 | 0.1 mL |
Product No. | Pack Size |
---|---|
07071019001 | 1.0 mL |
To order these products, please contact your Roche order management team.
CD35, also known as complement receptor type 1, is a monomeric single-pass type 1 membrane glycoprotein from complement activation (RCA) family. CD35 binds complement components C3b and C4b and has an inhibitory effect on complement activation by both the classical and alternative pathways. CD35 is expressed by glomerular podocytes, follicular dendritic cells, erythrocytes, and some leukocytes. Abnormal expression of this protein has been associated with follicular dendritic cell tumor, sarcoidosis, gallbladder carcinomas, mesangiocapillary glomerulonephritis, and systemic lupus erythematosus.
Figure above:
Human kidney stained with anti-CD35 antibody
Contents
Rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.
IHC Performance
Human Colon stained with anti-CD35 antibody |
Human Kidney stained with anti-CD35 antibody |
Human Spleen stained with anti-CD35 antibody |
Human Tonsil stained with anti-CD35 antibody |
Western Blot Analysis
Western Blot analysis of human tonsil lysate with anti-CD35 antibody
Product Details:
Technology |
Rabbit Monoclonal |
Clone Name |
SP124 |
Application |
IHC-P, WB |
Species Reactivity |
|
Tested |
Hu |
Predicted by homology |
N/A |
Isotype |
Rabbit IgG |
Immunogen |
Synthetic peptide derived from human CD35 protein. |
Cellular Localization |
Membrane |
Control Tissue |
Kidney, Tonsil |
Regulatory Rating |
Research Use Only (RUO) |
Entrez |
1378 |
Storage Requirement |
2-8°C |
Target Molecular Weight |
280 kDa |
Formulation |
Refer to Data Sheet |