Rabbit Anti-Human CD43 Monoclonal Antibody (Clone SP55)

For research use only. Not for use in diagnostics.

Product No.	Pack Size
06970982001	0.1 mL

Product No.	Pack Size
06971024001	1.0 mL

To order these products, please contact your Roche order management team.

Keywords: Antibodies, Rabbit Monoclonal

CD43 is one of the major glycoproteins of thymocytes and T lymphocytes. It plays a role in the physicochemical properties of the T cell surface and in lectin binding. CD43 presents carbohydrate ligands to selectins. It has an extended rodlike structure that could protrude above the glycocalyx of the cell and allow multiple glycan chains to be accessible for binding. The antigen is a counter receptor for SN/Siglec1. During T cell activation CD43 is actively removed from the T cell antigen presenting cell contact site suggesting a negative regulatory role in adaptive immune response. **Please contact us for availability**

Figure above:
Human Tonsil stained with anti-CD43 antibody

Contents

Rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.

IHC Performance


Human Tonsil stained with anti-CD43 antibody	Human Bladder Transitional Cell Carcinoma stained with anti-CD43 antibody	Human Thymus stained with anti-CD43 antibody	Human Spleen stained with anti-CD43 antibody.

Human Prostate stained with anti-CD43 antibody	Human Esophagus stained with anti-CD43 antibody	Human Endometrium stained with anti-CD43 antibody	Human Colon stained with anti-CD43 antibody

Human Colon Adenocarcinoma stained with anti-CD43 antibody	Human Lung stained with anti-CD43 antibody

Flow cytometric analysis

Flow cytometric analysis of rabbit anti-CD43 (SP55) antibody in Jurkat (green) compare to negative control of rabbit IgG (blue)

Western Blot analysis

Western Blot of of rabbit anti-CD43 (SP55) antibody

Product Details:

Technology	Rabbit Monoclonal
Clone Name	SP55
Application	IHC-P, WB, FACS
Species Reactivity
Tested	Hu
Predicted by homology	N/A
Isotype	Rabbit IgG
Immunogen	Synthetic peptide derived from the human CD43.
Cellular Localization	Membrane
Control Tissue	Tonsil
Regulatory Rating	Research Use Only (RUO)
Entrez	6693
Storage Requirement	2-8°C
Target Molecular Weight	95/115/135 kDa
Formulation	Refer to Data Sheet

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Rabbit Anti-Human CD43 Monoclonal Antibody (Clone SP55)