Rabbit Anti-Human CD43 Monoclonal Antibody (Clone SP55)
For research use only. Not for use in diagnostics.
Product No. | Pack Size |
---|---|
06970982001 | 0.1 mL |
Product No. | Pack Size |
---|---|
06971024001 | 1.0 mL |
To order these products, please contact your Roche order management team.
CD43 is one of the major glycoproteins of thymocytes and T lymphocytes. It plays a role in the physicochemical properties of the T cell surface and in lectin binding. CD43 presents carbohydrate ligands to selectins. It has an extended rodlike structure that could protrude above the glycocalyx of the cell and allow multiple glycan chains to be accessible for binding. The antigen is a counter receptor for SN/Siglec1. During T cell activation CD43 is actively removed from the T cell antigen presenting cell contact site suggesting a negative regulatory role in adaptive immune response. **Please contact us for availability**
Figure above:
Human Tonsil stained with anti-CD43 antibody
Contents
Rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.
IHC Performance
Human Tonsil stained with anti-CD43 antibody |
Human Bladder Transitional Cell Carcinoma stained with anti-CD43 antibody |
Human Thymus stained with anti-CD43 antibody |
Human Spleen stained with anti-CD43 antibody. |
Human Prostate stained with anti-CD43 antibody |
Human Esophagus stained with anti-CD43 antibody |
Human Endometrium stained with anti-CD43 antibody |
Human Colon stained with anti-CD43 antibody |
Human Colon Adenocarcinoma stained with anti-CD43 antibody |
Human Lung stained with anti-CD43 antibody |
Flow cytometric analysis
Flow cytometric analysis of rabbit anti-CD43 (SP55) antibody in Jurkat (green) compare to negative control of rabbit IgG (blue)
Western Blot analysis
Western Blot of of rabbit anti-CD43 (SP55) antibody
Product Details:
Technology |
Rabbit Monoclonal |
Clone Name |
SP55 |
Application |
IHC-P, WB, FACS |
Species Reactivity |
|
Tested |
Hu |
Predicted by homology |
N/A |
Isotype |
Rabbit IgG |
Immunogen |
Synthetic peptide derived from the human CD43. |
Cellular Localization |
Membrane |
Control Tissue |
Tonsil |
Regulatory Rating |
Research Use Only (RUO) |
Entrez |
6693 |
Storage Requirement |
2-8°C |
Target Molecular Weight |
95/115/135 kDa |
Formulation |
Refer to Data Sheet |