Rabbit Anti-Human CD68 Monoclonal Antibody (Clone SP251)

For research use only. Not for use in diagnostics.

Product No.	Pack Size
07298722001	0.1 mL

Product No.	Pack Size
07298803001	1.0 mL

To order these products, please contact your Roche order management team.

Keywords: Antibodies, Rabbit Monoclonal

CD68 is an intracellular glycoprotein mainly expressed on macrophages and monocytes. It could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. CD68 is also expressed by interdigitating reticulum cells in tonsil and some histiocytic lymphoma or histiocytosis, acute myeloid leukemia (AML) (M1-M5 types), and granulocytic sarcoma.

Figure above:
Human tonsil stained with anti-CD68 antibody

Contents

Rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.

IHC Performance

Human Tonsil stained with anti-CD68 antibody

Flow Cytometric Analysis

Flow cytometric analysis of rabbit anti-68 (SP251) antibody in Raji cells (green) compare to negative control of rabbit IgG (blue)

Product Details:

Technology	Rabbit Monoclonal
Clone Name	SP251
Application	IHC-P, FACS
Species Reactivity
Tested	Hu
Predicted by homology	N/A
Isotype	Rabbit IgG
Immunogen	Synthetic peptide derived from the internal region of the human CD68 protein.
Cellular Localization	Cytoplasm
Control Tissue	Tonsil
Regulatory Rating	Research Use Only (RUO)
Entrez	968
Storage Requirement	2-8°C
Target Molecular Weight	37 kDa (calculated); 110 kDa (glycosylation form)
Formulation	Refer to Data Sheet

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