Rabbit Anti-Human CD8 Monoclonal Antibody (Clone SP16)

For research use only. Not for use in diagnostics.

Product No.	Pack Size
05493846001	0.1 mL

Product No.	Pack Size
05298709001	1.0 mL

To order these products, please contact your Roche order management team.

Keywords: Antibodies, Rabbit Monoclonal

CD8 molecule consists of two chains, termed a and ß chain, which are expressed as a disulphide-linked a/ß heterdimer or as an a/a homodimer on T cell subset, thymocytes and NK cells. The majority of CD8+ T cells express CD8 as a/ß heterdimer. CD8 functions as a coreceptor in concert with TCR for binding the MHC class I/peptide complex. The HIV-2 envelope glycoprotein binds CD8 a chain (but not ß chain).

Figure above:
Human Endometrium stained with anti-CD8 antibody

Contents

Rabbit monoclonal antibody supplied as tissue culture supernatant in TBS/1% BSA buffer pH 7.5 with less than 0.1% sodium azide.

IHC Performance


Human Tonsil stained with anti-CD8 antibody	Human Fallopian Tube stained with anti-CD8 antibody	Human Prostate stained with anti-CD8 antibody	Human Thyroid stained with anti-CD8 antibody

Human Esophagus stained with anti-CD8 antibody	Human Colon Adenocarcinoma stained with anti-CD8 antibody	Human Thymus stained with anti-CD8 antibody	Human Reactive Lymph Node stained with anti-CD8 antibody

Human Spleen stained with anti-CD8 antibody	Human HK Lymphoma stained with anti-CD8 antibody	Human B Cell Lymphoma stained with anti-CD8 antibody	Human Colon stained with anti-CD8 antibody

Human Cervix stained with anti-CD8 antibody	Human Endometrium stained with anti-CD8 antibody

Product Details:

Technology	Rabbit Monoclonal
Clone Name	SP16
Application	IHC-P
Species Reactivity
Tested	Hu
Predicted by homology	N/A
Isotype	Rabbit IgG
Immunogen	Synthetic peptide corresponding to C-terminus of alpha chain of the human CD8 molecule.
Cellular Localization	Membrane
Control Tissue	Tonsil
Regulatory Rating	Research Use Only (RUO)
Entrez	925
Storage Requirement	2-8°C
Target Molecular Weight	32 kDa
Formulation	Refer to Data Sheet

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Rabbit Anti-Human CD8 Monoclonal Antibody (Clone SP16)