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Rabbit Anti-Human Cdk2 Monoclonal Antibody (Clone SP80 )

For research use only. Not for use in diagnostics.

Product No. Pack Size
06971946001 0.1 mL
Product No. Pack Size
06971989001 1.0 mL

To order these products, please contact your Roche order management team.

CDK2 is a member of the Ser/Thr protein kinase family. It is highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2. It is a catalytic subunit of the cyclin-dependent protein kinase complex, whose activity is restricted to the G1-S phase, and is essential for cell cycle G1/S phase transition. This protein associates with and is regulated by the regulatory subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A) and p27Kip1 (CDKN1B). Its activity is also regulated by protein phosphorylation. Two alternatively spliced variants and multiple transcription initiation sites of this gene have been reported.

Figure above:
Human tonsil stained with anti-Cdk2 antibody

Contents

Rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.

IHC Performance

 

Human tonsil stained with anti-Cdk2 antibody

Human tonsil stained with anti-Cdk2 antibody




Western Blot Analysis

 

 

Western Blot analysis of HeLa cell lysate with Cdk2 antibody
Western Blot analysis of HeLa cell lysate with Cdk2 antibody

Product Details:

 

Technology

Rabbit Monoclonal

Clone Name

SP80

Application

IHC-P, WB

Species Reactivity

 

Tested

Hu

Predicted by homology

Bv, Hm, Ms, Rt

Isotype

Rabbit IgG

Immunogen

Synthetic peptide corresponding to C-terminus of human CDK2 protein.

Cellular Localization

Cytoplasm, Nucleus

Control Tissue

Tonsil

Regulatory Rating

Research Use Only (RUO)

Entrez

1017

Storage Requirement

2-8°C

Target Molecular Weight

33 kDa

Formulation

Refer to Data Sheet