Rabbit Anti-Human Cleaved PTEN (D301) Monoclonal Antibody (Clone SP227)

For research use only. Not for use in diagnostics.

Product No. Pack Size
07111274001 0.1 mL
Product No. Pack Size
07111304001 1.0 mL

To order these products, please contact your Roche order management team.

Phosphatidylinositol-3, 4, 5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase (PTEN) is a tumor suppressor and can be cleaved by caspase-3 at multiple sites (D301, D371, D375, and D384) during apoptosis. The generation of cleaved PTEN (D301) is an indicator of apoptosis. **Please contact us for availability**

Figure above:
Human tonsil stained with anti-cleaved PTEN (D301) antibody

Contents

Rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.

IHC Performance

 

Human Tonsil stained with anti-cleaved PTEN (D301) antibody

Human Tonsil stained with anti-cleaved PTEN (D301) antibody



Western Blot Analysis

 

Western Blot analysis of anti-cleaved PTEN (D301) antibody

Western Blot analysis of anti-cleaved PTEN (D301) antibody

Product Details:

 

Technology

Rabbit Monoclonal

Clone Name

SP227

Application

IHC-P

Species Reactivity

 

   Tested

Hu

   Predicted by homology

 

Isotype

Rabbit IgG

Immunogen

Synthetic peptide derived from human PTEN protein with D301 cleaved site.

Cellular Localization

 

Control Tissue

Tonsil, NIH3T3 Cells Treated with Staurosporine

Regulatory Rating

Research Use Only (RUO)

Entrez

5728

Storage Requirement

2-8°C

Target Molecular Weight

30 kDa

Formulation

Refer to Data Sheet