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Rabbit Anti-Human Cyclin E1 Monoclonal Antibody (Clone SP146)

For research use only. Not for use in diagnostics.

Product No. Pack Size
06974368001 0.1 mL
Product No. Pack Size
06974392001 1.0 mL

To order these products, please contact your Roche order management team.

G1/S-specific cyclin-E1 (Cyclin E) is a regulatory subunit of CDK2 during G1 phase and controls G1/S transition during the mammalian cell cycle. The Cyclin E/CDK2 complex phosphorylates p27Kip1 and truncated variant isoforms of cyclin E can phosphorylate histone H1 to initiate DNA synthesis. Multiple isoforms of cyclin E are identified in tumor tissues. **Please contact us for availability**

Figure above:
Human Colon stained with anti-Cyclin E1 antibody

Contents

Rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.

IHC Performance

 

Human Cervical Squamous Cell Carcinoma stained with anti-Cyclin E1 antibody

Human Colon Adenocarcinoma stained with anti-Cyclin E1 antibody

Human Colon stained with anti-Cyclin E1 antibody

Human Ovarian Adenocarcinoma stained with anti-Cyclin E1 antibody

Human Cervical Squamous Cell Carcinoma stained with anti-Cyclin E1 antibody

Human Colon Adenocarcinoma stained with anti-Cyclin E1 antibody

Human Colon stained with anti-Cyclin E1 antibody

Human Ovarian Adenocarcinoma stained with anti-Cyclin E1 antibody

Human Placenta stained with anti-Cyclin E1 antibody

Human Stomach Adenocarcinoma stained with anti-Cyclin E1 antibody

Human Stomach stained with anti-Cyclin E1 antibody

Human Placenta stained with anti-Cyclin E1 antibody

Human Stomach Adenocarcinoma stained with anti-Cyclin E1 antibody

Human Stomach stained with anti-Cyclin E1 antibody

Product Details:

 

Technology

Rabbit Monoclonal

Clone Name

SP146

Application

IHC-P

Species Reactivity

 

   Tested

Hu

   Predicted by homology

N/A

Isotype

Rabbit IgG

Immunogen

Near the C-terminus of the human cyclin E1 protein.

Cellular Localization

Nucleus

Control Tissue

Colon, Colon Carcinoma, Placenta

Regulatory Rating

Research Use Only (RUO)

Entrez

898

Storage Requirement

2-8°C

Target Molecular Weight

50 kDa

Formulation

Refer to Data Sheet