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Rabbit Anti-Human E-Cadherin Monoclonal Antibody (Clone SP64)

For research use only. Not for use in diagnostics.

Product No. Pack Size
06971318001 0.1 mL
Product No. Pack Size
06971342001 1.0 mL

To order these products, please contact your Roche order management team.

E-cadherin (uvomorulin, cell-CAM120/80) is a calcium dependent cell adhesion molecule expressed predominately in epithelial tissues. It plays an important role in the growth and development of cells via the mechanisms of control of tissue architecture and the maintenance of tissue integrity. Numerous studies have demonstrated that reduction and/or loss of E-cadherin expression in carcinomas correlates positively with the potential of these tumors for invasion and metastasis. **Please contact us for availability**

Figure above:
Human Breast Carcinoma stained with anti-Cadherin-E/E-Cadherin antibody

Contents

Rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.

IHC Performance

 

Human Breast Carcinoma stained with anti-Cadherin-E/E-cadherin antibody

Human prostate stained with anti-cadherin-E/E-cadherin antibody

Human skin squamous cell carcinoma stained with anti-cadherin-E/E-Cadherin antibody

Human skin stained with anti-cadherin-E/E-cadherin antibody



Western Blot Analysis

 


Western Blot analysis of anti-cadherin-E/E-cadherin antibody

Product Details:

 

Technology

Rabbit Monoclonal

Clone Name

SP64

Application

IHC-P, WB

Species Reactivity

 

   Tested

Hu

   Predicted by homology

N/A

Isotype

Rabbit IgG

Immunogen

Recombinant protein encoding aa 600-707 of human cadherin-E.

Cellular Localization

Membrane

Control Tissue

Breast Carcinoma, Colon

Regulatory Rating

Research Use Only (RUO)

Entrez

999

Storage Requirement

2-8°C

Target Molecular Weight

135 kDa

Formulation

Refer to Data Sheet