Rabbit Anti-Human ERCC1 Monoclonal Antibody (Clone SP68)
For research use only. Not for use in diagnostics.
Product No. | Pack Size |
---|---|
06971474001 | 0.1 mL |
Product No. | Pack Size |
---|---|
06971512001 | 1.0 mL |
To order these products, please contact your Roche order management team.
The mammalian ERCC1 (Excision Repair Cross Complementing) polypeptide is required for nucleotide excision repair (NER) of damaged DNA and is homologous to Saccharomyces cerevisiae RAD10, which functions in repair and mitotic intrachromosomal recombination. NER mechanism involves dual incisions on both sides of the damage catalyzed by two nucleases. In mammalian cells XPG cleaves 3' of the DNA lesion while the ERCC1-XPF complex makes the 5' incision.
Figure above:
Human Lung Carcinoma stained with anti-ERCC1 antibody
Contents
Rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.
IHC Performance
Human Lung Carcinoma stained with anti-ERCC1 antibody |
Human Bladder Transitional Cell Carcinoma stained with anti-ERCC1 antibody |
Human Breast Ductal Carcinoma stained with anti-ERCC1 antibody |
Human Colon Adenocarcinoma stained with anti-ERCC1 antibody |
Human Colon stained with anti-ERCC1 antibody |
Human Hepatocellular Carcinoma stained with anti-ERCC1 antibody |
Human Lung Adenocarcinoma stained with anti-ERCC1 antibody |
Human Prostate Adenocarcinoma stained with anti-ERCC1 antibody |
Human Renal Cell Carcinoma stained with anti-ERCC1 antibody |
Human Skin Squamous Cell Carcinoma stained with anti-ERCC1 antibody |
Human Testis stained with anti-ERCC1 antibody |
Product Details:
Technology |
Rabbit Monoclonal |
Clone Name |
SP68 |
Application |
IHC-P |
Species Reactivity |
|
Tested |
Hu |
Predicted by homology |
Bv, Hm, Ms, Pg, Rt |
Isotype |
Rabbit IgG |
Immunogen |
Recombinant human ERCC1 protein. |
Cellular Localization |
Nucleus |
Control Tissue |
Colon, Non-Small Cell Lung Carcinoma |
Regulatory Rating |
Research Use Only (RUO) |
Entrez |
2067 |
Storage Requirement |
2-8°C |
Target Molecular Weight |
33-36 kDa |
Formulation |
Refer to Data Sheet |