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Rabbit Anti-Human FoxP1 Monoclonal Antibody (Clone SP133)

For research use only. Not for use in diagnostics.

Product No. Pack Size
06973922001 0.1 mL
Product No. Pack Size
06973965001 1.0 mL

To order these products, please contact your Roche order management team.

Forkhead box protein P1 (FOXP1) is a transcriptional repressor that plays an important role in the development of the brain and lung in mammals. The gene encoding this protein may act as a tumor suppressor as it is lost in several tumor types and maps to a chromosomal region (3p14.1) reported to contain a tumor suppressor gene. It is essential transcriptional regulator of B cell development. PAX5/FOXP1 translocation t(9;3)(p13;p14.1) is found in acute lymphoblastic leukemia. FOXP1 is positive in subset of diffuse large B-cell lymphoma and mucosa-associated lymphoid tissue lymphomas. **Please contact us for availability**

Figure above:
Human tonsil stained with anti-FoxP1 antibody

Contents

Rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.

IHC Performance

 

Human Tonsil stained with anti-FoxP1 antibody

Human Tonsil stained with anti-FoxP1 antibody



Flow Cytometric Analysis

 

Flow cytometric analysis of rabbit anti-FOXP1 (SP133) antibody in MOLT4 (green) compare to negative control of rabbit IgG (blue)

Flow cytometric analysis of rabbit anti-FOXP1 (SP133) antibody in MOLT4 (green) compare to negative control of rabbit IgG (blue)



Western Blot Analysis

 

Western Blot analysis of MCF7 cell lysate

Western Blot analysis of MCF7 cell lysate

Product Details:

 

Technology

Rabbit Monoclonal

Clone Name

SP133

Application

IHC-P, WB, FACS

Species Reactivity

 

   Tested

Hu

   Predicted by homology

Ms, Fg

Isotype

Rabbit IgG

Immunogen

Synthetic peptide corresponding to the C-terminus of human FOXP1 protein.

Cellular Localization

Nucleus

Control Tissue

Tonsil

Regulatory Rating

Research Use Only (RUO)

Entrez

27086

Storage Requirement

2-8°C

Target Molecular Weight

55-75 kDa (four isoforms)

Formulation

Refer to Data Sheet