Rabbit Anti-Human FoxP1 Monoclonal Antibody (Clone SP133)
For research use only. Not for use in diagnostics.
| Product No. | Pack Size |
|---|---|
| 06973922001 | 0.1 mL |
| Product No. | Pack Size |
|---|---|
| 06973965001 | 1.0 mL |
To order these products, please contact your Roche order management team.
Forkhead box protein P1 (FOXP1) is a transcriptional repressor that plays an important role in the development of the brain and lung in mammals. The gene encoding this protein may act as a tumor suppressor as it is lost in several tumor types and maps to a chromosomal region (3p14.1) reported to contain a tumor suppressor gene. It is essential transcriptional regulator of B cell development. PAX5/FOXP1 translocation t(9;3)(p13;p14.1) is found in acute lymphoblastic leukemia. FOXP1 is positive in subset of diffuse large B-cell lymphoma and mucosa-associated lymphoid tissue lymphomas. **Please contact us for availability**
Figure above:
Human tonsil stained with anti-FoxP1 antibody
Contents
Rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.
IHC Performance
|
Human Tonsil stained with anti-FoxP1 antibody |
Flow Cytometric Analysis
Flow cytometric analysis of rabbit anti-FOXP1 (SP133) antibody in MOLT4 (green) compare to negative control of rabbit IgG (blue)
Western Blot Analysis
Western Blot analysis of MCF7 cell lysate
Product Details:
Technology |
Rabbit Monoclonal |
Clone Name |
SP133 |
Application |
IHC-P, WB, FACS |
Species Reactivity |
|
Tested |
Hu |
Predicted by homology |
Ms, Fg |
Isotype |
Rabbit IgG |
Immunogen |
Synthetic peptide corresponding to the C-terminus of human FOXP1 protein. |
Cellular Localization |
Nucleus |
Control Tissue |
Tonsil |
Regulatory Rating |
Research Use Only (RUO) |
Entrez |
27086 |
Storage Requirement |
2-8°C |
Target Molecular Weight |
55-75 kDa (four isoforms) |
Formulation |
Refer to Data Sheet |
Associated Products
Instructions for Use (IFU)
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