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Rabbit Anti-Human FoxP3 Monoclonal Antibody (Clone SP97)

For research use only. Not for use in diagnostics.

Product No. Pack Size
06972659001 0.1 mL
Product No. Pack Size
06972683001 1.0 mL

To order these products, please contact your Roche order management team.

FOXP3 (a 431 amino acid protein) is a member of the forkhead/winged-helix family of transcriptional regulators and is highly conserved across mammals. FOXP3 is essential for normal immune homeostasis. FOXP3 is stably and constitutively expressed at a high level in CD25 + CD4 positive regulatory T cells, at a low level in CD4 positive/CD25 negative cells, and is absent in CD4 negative/CD8 positive T cells. FOXP3 may be a master regulatory gene and a more specific marker of regulatory T cells than other T cells.

Figure above:
Human Tonsil stained with anti-FOXP3 antibody

Contents

Rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.

IHC Performance

 

Human Tonsil stained with anti-FoxP3 antibody

Human B-Cell Lymphoma stained with anti-FoxP3 antibody

Human Bladder stained with anti-FoxP3 antibody

Human Bladder Transitional Cell Carcinoma stained with anti-FoxP3 antibody

Human Tonsil stained with anti-FoxP3 antibody

Human B-Cell Lymphoma stained with anti-FoxP3 antibody

Human Bladder stained with anti-FoxP3 antibody

Human Bladder Transitional Cell Carcinoma stained with anti-FoxP3 antibody

Human Cervical Squamous Cell Carcinoma stained with anti-FoxP3 antibody

Human Colon Adenocarcinoma stained with anti-FoxP3 antibody

Human Colon stained with anti-FoxP3 antibody

Human Lymph Node stained with anti-FoxP3 antibody

Human Cervical Squamous Cell Carcinoma stained with anti-FoxP3 antibody

Human Colon Adenocarcinoma stained with anti-FoxP3 antibody

Human Colon stained with anti-FoxP3 antibody

Human Lymph Node stained with anti-FoxP3 antibody

Human Pancreatic Adenocarcinoma stained with anti-FoxP3 antibody

Human Stomach Adenocarcinoma stained with anti-FoxP3 antibody

Human Thymus stained with anti-FoxP3 antibody

Human Tonsil stained with anti-FoxP3 antibody

Human Pancreatic Adenocarcinoma stained with anti-FoxP3 antibody

Human Stomach Adenocarcinoma stained with anti-FoxP3 antibody

Human Thymus stained with anti-FoxP3 antibody

Human Tonsil stained with anti-FoxP3 antibody

Product Details:

 

Technology

Rabbit Monoclonal

Clone Name

SP97

Application

IHC-P

Species Reactivity

 

   Tested

Hu

   Predicted by homology

Bv, Dg, Ms, Pg, Rt

Isotype

Rabbit IgG

Immunogen

Synthetic peptide corresponding to C-terminus of human FOXP3 protein.

Cellular Localization

Nucleus

Control Tissue

Tonsil

Regulatory Rating

Research Use Only (RUO)

Entrez

90543

Storage Requirement

2-8°C

Target Molecular Weight

50 kDa

Formulation

Refer to Data Sheet