Rabbit Anti-Human FoxP3 Monoclonal Antibody (Clone SP97)
For research use only. Not for use in diagnostics.
| Product No. | Pack Size |
|---|---|
| 06972659001 | 0.1 mL |
| Product No. | Pack Size |
|---|---|
| 06972683001 | 1.0 mL |
To order these products, please contact your Roche order management team.
FOXP3 (a 431 amino acid protein) is a member of the forkhead/winged-helix family of transcriptional regulators and is highly conserved across mammals. FOXP3 is essential for normal immune homeostasis. FOXP3 is stably and constitutively expressed at a high level in CD25 + CD4 positive regulatory T cells, at a low level in CD4 positive/CD25 negative cells, and is absent in CD4 negative/CD8 positive T cells. FOXP3 may be a master regulatory gene and a more specific marker of regulatory T cells than other T cells.
Figure above:
Human Tonsil stained with anti-FOXP3 antibody
Contents
Rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.
IHC Performance
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Human Tonsil stained with anti-FoxP3 antibody |
Human B-Cell Lymphoma stained with anti-FoxP3 antibody |
Human Bladder stained with anti-FoxP3 antibody |
Human Bladder Transitional Cell Carcinoma stained with anti-FoxP3 antibody |
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Human Cervical Squamous Cell Carcinoma stained with anti-FoxP3 antibody |
Human Colon Adenocarcinoma stained with anti-FoxP3 antibody |
Human Colon stained with anti-FoxP3 antibody |
Human Lymph Node stained with anti-FoxP3 antibody |
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Human Pancreatic Adenocarcinoma stained with anti-FoxP3 antibody |
Human Stomach Adenocarcinoma stained with anti-FoxP3 antibody |
Human Thymus stained with anti-FoxP3 antibody |
Human Tonsil stained with anti-FoxP3 antibody |
Product Details:
Technology |
Rabbit Monoclonal |
Clone Name |
SP97 |
Application |
IHC-P |
Species Reactivity |
|
Tested |
Hu |
Predicted by homology |
Bv, Dg, Ms, Pg, Rt |
Isotype |
Rabbit IgG |
Immunogen |
Synthetic peptide corresponding to C-terminus of human FOXP3 protein. |
Cellular Localization |
Nucleus |
Control Tissue |
Tonsil |
Regulatory Rating |
Research Use Only (RUO) |
Entrez |
90543 |
Storage Requirement |
2-8°C |
Target Molecular Weight |
50 kDa |
Formulation |
Refer to Data Sheet |
Associated Products
Instructions for Use (IFU)
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