Rabbit Anti-Human FoxP3 Monoclonal Antibody (Clone SP97)

For research use only. Not for use in diagnostics.

Product No.	Pack Size
06972659001	0.1 mL

Product No.	Pack Size
06972683001	1.0 mL

To order these products, please contact your Roche order management team.

Keywords: Antibodies, Rabbit Monoclonal

FOXP3 (a 431 amino acid protein) is a member of the forkhead/winged-helix family of transcriptional regulators and is highly conserved across mammals. FOXP3 is essential for normal immune homeostasis. FOXP3 is stably and constitutively expressed at a high level in CD25 + CD4 positive regulatory T cells, at a low level in CD4 positive/CD25 negative cells, and is absent in CD4 negative/CD8 positive T cells. FOXP3 may be a master regulatory gene and a more specific marker of regulatory T cells than other T cells.

Figure above:
Human Tonsil stained with anti-FOXP3 antibody

Contents

Rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.

IHC Performance


Human Tonsil stained with anti-FoxP3 antibody	Human B-Cell Lymphoma stained with anti-FoxP3 antibody	Human Bladder stained with anti-FoxP3 antibody	Human Bladder Transitional Cell Carcinoma stained with anti-FoxP3 antibody

Human Cervical Squamous Cell Carcinoma stained with anti-FoxP3 antibody	Human Colon Adenocarcinoma stained with anti-FoxP3 antibody	Human Colon stained with anti-FoxP3 antibody	Human Lymph Node stained with anti-FoxP3 antibody

Human Pancreatic Adenocarcinoma stained with anti-FoxP3 antibody	Human Stomach Adenocarcinoma stained with anti-FoxP3 antibody	Human Thymus stained with anti-FoxP3 antibody	Human Tonsil stained with anti-FoxP3 antibody

Product Details:

Technology	Rabbit Monoclonal
Clone Name	SP97
Application	IHC-P
Species Reactivity
Tested	Hu
Predicted by homology	Bv, Dg, Ms, Pg, Rt
Isotype	Rabbit IgG
Immunogen	Synthetic peptide corresponding to C-terminus of human FOXP3 protein.
Cellular Localization	Nucleus
Control Tissue	Tonsil
Regulatory Rating	Research Use Only (RUO)
Entrez	90543
Storage Requirement	2-8°C
Target Molecular Weight	50 kDa
Formulation	Refer to Data Sheet

Associated Products

Rabbit Anti-Human B7-H3/CD276 Monoclonal Antibody (Clone SP206) Read more

Rabbit Anti-Human CD278 Monoclonal Antibody (Clone SP98 ) Read more

Rabbit Anti-Human IDO-1 Monoclonal Antibody (Clone SP260) Read more

Rabbit Anti-Human OX40 Monoclonal Antibody (Clone SP195) Read more

Rabbit Anti-Human PD-1/CD279 Monoclonal Antibody (Clone SP269) Read more

Rabbit Anti-Human PD-L1/CD274 Monoclonal Antibody (Clone SP142) Read more

Products are for life science research only. Not for use in diagnostic procedures unless otherwise indicated. This website contains information on products which is targeted to a wide range of audiences and could contain product details or information otherwise not accessible or valid in your country. Please be aware that we do not take any responsibility for accessing such information which may not comply with any valid legal process, regulation, registration or usage in the country of your origin.