Rabbit Anti-Human GPNMB Monoclonal Antibody (Clone SP299)
For research use only. Not for use in diagnostics.
| Product No. | Pack Size |
|---|---|
| 07747837001 | 0.1 mL |
| Product No. | Pack Size |
|---|---|
| 07747853001 | 1.0 mL |
To order these products, please contact your Roche order management team.
Transmembrane glycoprotein NMB (GPNMB) is a transmembrane glycoprotein that normally functions in the cell differentiation. It is mostly expressed in tissue macrophages and is overexpressed in some tumors from lung, cervix, breast, prostate, and melanoma.
Figure above:
Human tonsil stained with anti-GPNMB (SP299) antibody
Contents
Rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.
IHC Performance
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Human Cervical squamous cell carcinoma stained with ani-GPNMB antibody |
Human Colon stained with ani-GPNMB antibody |
Human Lung squamous cell carcinoma stained with ani-GPNMB antibody |
Human Lung stained with ani-GPNMB antibody |
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Human reactive lymph node stained with ani-GPNMB antibody |
Human Tonsil stained with anti-GPNMB (SP299) antibody |
Flow Cytometric Analysis
Flow cytometric analysis of anti-GPNMB (SP299) antibody in A375 cells (green) compare to negative control of rabbit IgG (blue)
Western Blot Analysis
Western blot analysis of A375 cell lysate with anti-GPNMB (SP299) antibody
Product Details:
Technology |
Rabbit Monoclonal |
Clone Name |
SP299 |
Application |
IHC-P, WB, FACS |
Species Reactivity |
|
Tested |
Hu |
Predicted by homology |
N/A |
Isotype |
Rabbit IgG |
Immunogen |
Recombinant human GPNMB protein. |
Cellular Localization |
Cytoplasm, Membrane |
Control Tissue |
Tonsil |
Regulatory Rating |
Research Use Only (RUO) |
Entrez |
10457 |
Storage Requirement |
2-8°C |
Target Molecular Weight |
95 kDa |
Formulation |
Refer to Data Sheet |
Instructions for Use (IFU)
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