Rabbit Anti-Human GPNMB Monoclonal Antibody (Clone SP299)

For research use only. Not for use in diagnostics.

Product No.	Pack Size
07747837001	0.1 mL

Product No.	Pack Size
07747853001	1.0 mL

To order these products, please contact your Roche order management team.

Keywords: Antibodies, Rabbit Monoclonal

Transmembrane glycoprotein NMB (GPNMB) is a transmembrane glycoprotein that normally functions in the cell differentiation. It is mostly expressed in tissue macrophages and is overexpressed in some tumors from lung, cervix, breast, prostate, and melanoma.

Figure above:
Human tonsil stained with anti-GPNMB (SP299) antibody

Contents

Rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.

IHC Performance


Human Cervical squamous cell carcinoma stained with ani-GPNMB antibody	Human Colon stained with ani-GPNMB antibody	Human Lung squamous cell carcinoma stained with ani-GPNMB antibody	Human Lung stained with ani-GPNMB antibody

Human reactive lymph node stained with ani-GPNMB antibody	Human Tonsil stained with anti-GPNMB (SP299) antibody

Flow Cytometric Analysis

Flow cytometric analysis of anti-GPNMB (SP299) antibody in A375 cells (green) compare to negative control of rabbit IgG (blue)

Western Blot Analysis

Western blot analysis of A375 cell lysate with anti-GPNMB (SP299) antibody

Product Details:

Technology	Rabbit Monoclonal
Clone Name	SP299
Application	IHC-P, WB, FACS
Species Reactivity
Tested	Hu
Predicted by homology	N/A
Isotype	Rabbit IgG
Immunogen	Recombinant human GPNMB protein.
Cellular Localization	Cytoplasm, Membrane
Control Tissue	Tonsil
Regulatory Rating	Research Use Only (RUO)
Entrez	10457
Storage Requirement	2-8°C
Target Molecular Weight	95 kDa
Formulation	Refer to Data Sheet

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