LifeScience
Rabbit Anti-Human GPNMB Monoclonal Antibody (Clone SP299)

Rabbit Anti-Human GPNMB Monoclonal Antibody (Clone SP299)

For research use only. Not for use in diagnostics.

Product No. Pack Size
07747837001 0.1 mL
Contact Us
Product No. Pack Size
07747853001 1.0 mL

To order these products, please contact your Roche order management team.

Keywords: Antibodies, Rabbit Monoclonal

Transmembrane glycoprotein NMB (GPNMB) is a transmembrane glycoprotein that normally functions in the cell differentiation. It is mostly expressed in tissue macrophages and is overexpressed in some tumors from lung, cervix, breast, prostate, and melanoma.

Figure above:
Human tonsil stained with anti-GPNMB (SP299) antibody

Contents

Rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.

IHC Performance

 

Human Cervical squamous cell carcinoma stained with ani-GPNMB antibody

Human Colon stained with ani-GPNMB antibody.

Human Lung squamous cell carcinoma stained with ani-GPNMB antibody

Human Lung stained with ani-GPNMB antibody

Human Cervical squamous cell carcinoma stained with ani-GPNMB antibody

Human Colon stained with ani-GPNMB antibody

Human Lung squamous cell carcinoma stained with ani-GPNMB antibody

Human Lung stained with ani-GPNMB antibody

Human reactive lymph node stained with ani-GPNMB antibody

Human Tonsil stained with anti-GPNMB (SP299) antibody

Human reactive lymph node stained with ani-GPNMB antibody

Human Tonsil stained with anti-GPNMB (SP299) antibody



Flow Cytometric Analysis

 

Flow cytometric analysis of anti-GPNMB (SP299) antibody in A375 cells (green) compare to negative control of rabbit IgG (blue)

Flow cytometric analysis of anti-GPNMB (SP299) antibody in A375 cells (green) compare to negative control of rabbit IgG (blue)



Western Blot Analysis

 

Western blot analysis of A375 cell lysate with anti-GPNMB (SP299) antibody

Western blot analysis of A375 cell lysate with anti-GPNMB (SP299) antibody

Product Details:

 

Technology

Rabbit Monoclonal

Clone Name

SP299

Application

IHC-P, WB, FACS

Species Reactivity

  

   Tested

Hu

   Predicted by homology

N/A

Isotype

Rabbit IgG

Immunogen

Recombinant human GPNMB protein.

Cellular Localization

Cytoplasm, Membrane

Control Tissue

Tonsil

Regulatory Rating

Research Use Only (RUO)

Entrez

10457

Storage Requirement

2-8°C

Target Molecular Weight

95 kDa

Formulation

Refer to Data Sheet