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Rabbit Anti-Human IDO-1 Monoclonal Antibody (Clone SP260)

For research use only. Not for use in diagnostics.

Product No. Pack Size
07392478001 0.1 mL
Product No. Pack Size
07392494001 1.0 mL

To order these products, please contact your Roche order management team.

Indoleamine-pyrrole 2,3-dioxygenase (IDO) is an enzyme that catalyzes the degradation of the essential amino acid L-tryptophan to N-formyl-D-kynurenine. High levels of IDO are seen in antigen presenting cells and some tumor cells.

Figure above:
Human tonsil stained with anti-IDO-1 antibody

Contents

Rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.

IHC Performance

 

Human Colon stained with anti-IDO-1 antibody

Human Endometrial adenocarcinoma stained with anti-IDO-1 antibody

Human Ovarian adenocarcinoma stained with anti-IDO-1 antibody

Human Pancreatic adenocarcinoma stained with anti-IDO-1 antibody

Human Colon stained with anti-IDO-1 antibody

Human Endometrial adenocarcinoma stained with anti-IDO-1 antibody

Human Ovarian adenocarcinoma stained with anti-IDO-1 antibody

Human Pancreatic adenocarcinoma stained with anti-IDO-1 antibody

Human Stomach adenocarcinoma stained with anti-IDO-1 antibody

Human Thymus stained with aniti-IDO-1 antibody

Human Tonsil stained with anti-IDO-1 antibody

Human Stomach adenocarcinoma stained with anti-IDO-1 antibody

Human Thymus stained with aniti-IDO-1 antibody

Human Tonsil stained with anti-IDO-1 antibody



Flow Cytometric Analysis

 

Flow cytometric analysis of rabbit anti-IDO1 (SP260) antibody in HeLa treated with IFN-gamma cells (green) compare to negative control of rabbit IgG (blue)

Flow cytometric analysis of rabbit anti-IDO1 (SP260) antibody in HeLa treated with IFN-gamma cells (green) compare to negative control of rabbit IgG (blue)

Product Details:

 

Technology

Rabbit Monoclonal

Clone Name

SP260

Application

IHC-P, FACS

Species Reactivity

 

   Tested

Hu

   Predicted by homology

N/A

Isotype

Rabbit IgG

Immunogen

Synthetic peptide derived from the C-terminus of human IDO-1 protein.

Cellular Localization

Cytoplasm

Control Tissue

Tonsil

Regulatory Rating

Research Use Only (RUO)

Entrez

3620

Storage Requirement

2-8°C

Target Molecular Weight

45 kDa

Formulation

Refer to Data Sheet