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Rabbit Anti-Human J-chain Monoclonal Antibody (Clone SP105)

For research use only. Not for use in diagnostics.

Product No. Pack Size
06972969001 0.1 mL
Product No. Pack Size
06972993001 1.0 mL

To order these products, please contact your Roche order management team.

J chain is a small glycopeptide and is structurally unrelated to heavy or light chains, but is synthesized by all plasma cells that secrete polymeric immunoglobulins. J chain is linked to IgA and IgM by disulfide bonds, however, it has been detected in IgG- and IgD-containing cells. J chains are present in a large proportion of the immunoglobulin-positive cells in the germinal centers of the tonsil and lymph node. B cells secrete J chain at an early stage of differentiation with the expression persisting in those cells destined to produce IgA or IgM. **Please contact us for availability**

Figure above:
Human Tonsil stained with anti-J-chain antibody

Contents

Rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.

IHC Performance

 

Human Tonsil stained with anti-J-chain antibody

Human B Cell Lymphoma stained with anti-J-chain antibody

Human Colon Adenocarcinoma stained with anti-J-chain antibody

Human Colon stained with anti-J-chain antibody

Human Tonsil stained with anti-J-chain antibody

Human B Cell Lymphoma stained with anti-J-chain antibody

Human Colon Adenocarcinoma stained with anti-J-chain antibody

Human Colon stained with anti-J-chain antibody

Human HK Lymphoma stained with anti-J-chain antibody

Human Lymph Node stained with anti-J-chain antibody

Human Spleen stained with anti-J-chain antibody

Human Stomach Adenocarcinoma stained with anti-J-chain antibody

Human HK Lymphoma stained with anti-J-chain antibody

Human Lymph Node stained with anti-J-chain antibody

Human Spleen stained with anti-J-chain antibody

Human Stomach Adenocarcinoma stained with anti-J-chain antibody

Human Thymus stained with anti-J-chain antibody

Human Thyroid stained with anti-J-chain antibody

Human Thymus stained with anti-J-chain antibody

Human Thyroid stained with anti-J-chain antibody

Product Details:

 

Technology

Rabbit Monoclonal

Clone Name

SP105

Application

IHC-P

Species Reactivity

 

   Tested

Hu

   Predicted by homology

Hu, Ms

Isotype

Rabbit IgG

Immunogen

Synthetic peptide near the N-terminus of human actin-beta protein.

Cellular Localization

Cytoplasm

Control Tissue

Tonsil

Regulatory Rating

Research Use Only (RUO)

Entrez

3512

Storage Requirement

2-8°C

Target Molecular Weight

17 kDa

Formulation

Refer to Data Sheet