Rabbit Anti-Human Kappa Light Chain Monoclonal Antibody (Clone SP148)
For research use only. Not for use in diagnostics.
Product No. | Pack Size |
---|---|
06974457001 | 0.1 mL |
Product No. | Pack Size |
---|---|
06974481001 | 1.0 mL |
To order these products, please contact your Roche order management team.
Kappa light chains are polypeptide chains resided in the cell membrane and cytoplasmic regions of normal B cells and plasma cells. The combination of kappa light chains and heavy chains forms immunoglobulin molecules. There are two classes of light chains found in immunoglobulins, kappa light chains and lambda light chains. Individual lymphoid cell only contains a single light chain class. This clonal restriction may be used to indicate the polyclonal or monoclonal nature of B cell and plasma cell populations.The ratio of kappa to lambda is about 2:1. The level of kappa or lambda can be greatly elevated in serum of patients with multiple myeloma or other B cell malignancies. **Please contact us for availability**
Figure above:
Human tonsil stained with anti-kappa light chain antibody
Contents
Rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.
IHC Performance
Human B-Cell Lymphoma stained with anti-Kappa Light Chain antibody |
Human Colon stained with anti-Kappa Light Chain antibody |
Human Follicular Lymphoma stained with anti-Kappa Light Chain antibody |
Human Spleen stained with anti-Kappa Light Chain antibody |
Human Stomach stained with anti-Kappa Light Chain antibody |
Human Tonsil stained with anti-kappa light chain antibody |
Western Blot Analysis
Western Blot analysis of human spleen lysate with kappa light chain antibody
Product Details:
Technology |
Rabbit Monoclonal |
Clone Name |
SP148 |
Application |
IHC-P, WB |
Species Reactivity |
|
Tested |
Hu |
Predicted by homology |
N/A |
Isotype |
Rabbit IgG |
Immunogen |
Free kappa light chain from pooled human IgG lambda myeloma sera. |
Cellular Localization |
Cytoplasm |
Control Tissue |
Tonsil |
Regulatory Rating |
Research Use Only (RUO) |
Entrez |
3514 |
Storage Requirement |
2-8°C |
Target Molecular Weight |
25 kDa |
Formulation |
Refer to Data Sheet |