Rabbit Anti-Human Keratin 6 Monoclonal Antibody (Clone SP87)

For research use only. Not for use in diagnostics.

Product No.	Pack Size
06972250001	0.1 mL

Product No.	Pack Size
06972284001	1.0 mL

To order these products, please contact your Roche order management team.

Keywords: Antibodies, Rabbit Monoclonal

Keratins 6 and 16 are expressed in keratinocytes, which are undergoing rapid turnover in the suprabasal region (also known as hyperproliferation related keratins). Keratin 6 is found in hair follicles, neck squamous cell carcinomas, suprabasal cells of a variety of internal stratified epithelia, in epidermis, in both normal and hyperproliferative situations. Epidermal injury results in activation of keratinocytes which express CK6 and CK16. CK6 is strongly expressed in about 75% of head and neck squamous cell carcinomas. Expression of CK6 is particularly associated with differentiation. **Please contact us for availability**

Figure above:
Human Prostate Carcinoma stained with anti-Keratin 6 antibody

Contents

Rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.

IHC Performance


Human Prostate Carcinoma stained with anti-Keratin 6 antibody	Human Breast stained with anti-Keratin 6 antibody	Human Stomach stained with anti-Keratin 6 antibody	Human Prostate stained with anti-Keratin 6 antibody

Human Lung Squamous Cell Carcinoma stained with anti-Keratin 6 antibody	Human Rectal Adenocarcinoma stained with anti-Keratin 6 antibody	Human Bladder stained with anti-Keratin 6 antibody	Human Bladder Transitional Cell Carcinoma stained with anti-Keratin 6 antibody

Human Colon Adenocarcinoma stained with anti-Keratin 6 antibody	Human Ovarian Adenocarcinoma stained with anti-Keratin 6 antibody	Human Placenta stained with anti-Keratin 6 antibody

Flow Cytometric Analysis

Flow cytometric analysis of rabbit anti-Keratin 6 (SP87) antibody in A431 (green) compare to negative control of rabbit IgG (blue)

Western Blot Analysis

Western Blot analysis of rabbit anti-Keratin 6 (SP87) antibody

Product Details:

Technology	Rabbit Monoclonal
Clone Name	SP87
Application	IHC-P, WB, FACS
Species Reactivity
Tested	Hu
Predicted by homology	Bv
Isotype	Rabbit IgG
Immunogen	Synthetic peptide derived from C-terminus of human keratin 6 protein.
Cellular Localization	Cytoplasm
Control Tissue	Prostate Cancer, Skin
Regulatory Rating	Research Use Only (RUO)
Entrez	286887
Storage Requirement	2-8°C
Target Molecular Weight	60 kDa
Formulation	Refer to Data Sheet

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