Rabbit Anti-Human Keratin 6 Monoclonal Antibody (Clone SP87)
For research use only. Not for use in diagnostics.
Product No. | Pack Size |
---|---|
06972250001 | 0.1 mL |
Product No. | Pack Size |
---|---|
06972284001 | 1.0 mL |
To order these products, please contact your Roche order management team.
Keratins 6 and 16 are expressed in keratinocytes, which are undergoing rapid turnover in the suprabasal region (also known as hyperproliferation related keratins). Keratin 6 is found in hair follicles, neck squamous cell carcinomas, suprabasal cells of a variety of internal stratified epithelia, in epidermis, in both normal and hyperproliferative situations. Epidermal injury results in activation of keratinocytes which express CK6 and CK16. CK6 is strongly expressed in about 75% of head and neck squamous cell carcinomas. Expression of CK6 is particularly associated with differentiation. **Please contact us for availability**
Figure above:
Human Prostate Carcinoma stained with anti-Keratin 6 antibody
Contents
Rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.
IHC Performance
Human Prostate Carcinoma stained with anti-Keratin 6 antibody |
Human Breast stained with anti-Keratin 6 antibody |
Human Stomach stained with anti-Keratin 6 antibody |
Human Prostate stained with anti-Keratin 6 antibody |
Human Lung Squamous Cell Carcinoma stained with anti-Keratin 6 antibody |
Human Rectal Adenocarcinoma stained with anti-Keratin 6 antibody |
Human Bladder stained with anti-Keratin 6 antibody |
Human Bladder Transitional Cell Carcinoma stained with anti-Keratin 6 antibody |
Human Colon Adenocarcinoma stained with anti-Keratin 6 antibody |
Human Ovarian Adenocarcinoma stained with anti-Keratin 6 antibody |
Human Placenta stained with anti-Keratin 6 antibody |
Flow Cytometric Analysis
Flow cytometric analysis of rabbit anti-Keratin 6 (SP87) antibody in A431 (green) compare to negative control of rabbit IgG (blue)
Western Blot Analysis
Western Blot analysis of rabbit anti-Keratin 6 (SP87) antibody
Product Details:
Technology |
Rabbit Monoclonal |
Clone Name |
SP87 |
Application |
IHC-P, WB, FACS |
Species Reactivity |
|
Tested |
Hu |
Predicted by homology |
Bv |
Isotype |
Rabbit IgG |
Immunogen |
Synthetic peptide derived from C-terminus of human keratin 6 protein. |
Cellular Localization |
Cytoplasm |
Control Tissue |
Prostate Cancer, Skin |
Regulatory Rating |
Research Use Only (RUO) |
Entrez |
286887 |
Storage Requirement |
2-8°C |
Target Molecular Weight |
60 kDa |
Formulation |
Refer to Data Sheet |