Rabbit Anti-Human MCM2 Monoclonal Antibody (Clone SP85)
For research use only. Not for use in diagnostics.
Product No. | Pack Size |
---|---|
06972179001 | 0.1 mL |
Product No. | Pack Size |
---|---|
06972209001 | 1.0 mL |
To order these products, please contact your Roche order management team.
MCM2 (Mini chromosome maintenance protein 2) is involved in regulating DNA replication. MCM2 (also called CDCL1, mitotin and BM28), is a human nuclear protein that is crucial in the cell cycle, being involved in the onset of DNA replication and cell division. It is similar to members of the family of early S-phase proteins. Mincheva et al. (1994) mapped the gene to 3q21. From its localization, CDCL1 became a candidate for an oncogene affected by chromosomal breaks in acute myeloid leukemia (AML). **Please contact us for availability**
Figure above:
Human Rectal Carcinoma stained with anti-MCM2 antibody
Contents
Rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.
IHC Performance
Human Rectal Carcinoma stained with anti-MCM2 antibody |
Human Prostate stained with anti-MCM2 antibody |
Human Pancreas Adenocarcinoma stained with anti-MCM2 antibody |
Human Stomach stained with anti-MCM2 antibody |
Human Stomach Adenocarcinoma stained with anti-MCM2 antibody |
Human Prostate Adenocarcinoma stained with anti-MCM2 antibody |
Human Breast stained with anti-MCM2 antibody |
Human Breast Ductal Carcinoma stained with anti-MCM2 antibody |
Human Colon stained with anti-MCM2 antibody |
Human Colon Adenocarcinoma stained with anti-MCM2 antibody |
Human Skin stained with anti-MCM2 antibody |
Human Skin Squamous Cell Carcinoma stained with anti-MCM2 antibody |
Human Pancreas stained with anti-MCM2 antibody |
Flow Cytometric Analysis
Flow cytometric analysis of rabbit anti-MCM2 (SP85) antibody in HeLa (green) compare to negative control of rabbit IgG (blue)
Western Blot Analysis
Western Blot analysis of rabbit anti-MCM2 (SP85) antibody
Product Details:
Technology |
Rabbit Monoclonal |
Clone Name |
SP85 |
Application |
IHC-P, WB, FACS |
Species Reactivity |
|
Tested |
Hu |
Predicted by homology |
Bv, Dg, Fg, Ms, Rt |
Isotype |
Rabbit IgG |
Immunogen |
Synthetic peptide derived from internal region of human MCM2 protein. |
Cellular Localization |
Nucleus |
Control Tissue |
Rectal Carcinoma |
Regulatory Rating |
Research Use Only (RUO) |
Entrez |
4171 |
Storage Requirement |
2-8°C |
Target Molecular Weight |
130 kDa |
Formulation |
Refer to Data Sheet |