Welcome

You've successfully logged in

This website uses cookies to provide you with a more responsive and personalized service. In order to proceed to login, however, you must formally accept our cookie policy. Please read our cookie & privacy policies for more information.

Rabbit Anti-Human MCM2 Monoclonal Antibody (Clone SP85)

For research use only. Not for use in diagnostics.

Product No. Pack Size
06972179001 0.1 mL
Product No. Pack Size
06972209001 1.0 mL

To order these products, please contact your Roche order management team.

MCM2 (Mini chromosome maintenance protein 2) is involved in regulating DNA replication. MCM2 (also called CDCL1, mitotin and BM28), is a human nuclear protein that is crucial in the cell cycle, being involved in the onset of DNA replication and cell division. It is similar to members of the family of early S-phase proteins. Mincheva et al. (1994) mapped the gene to 3q21. From its localization, CDCL1 became a candidate for an oncogene affected by chromosomal breaks in acute myeloid leukemia (AML). **Please contact us for availability**

Figure above:
Human Rectal Carcinoma stained with anti-MCM2 antibody

Contents

Rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.

IHC Performance

 

Human Rectal Carcinoma stained with anti-MCM2 antibody

Human Prostate stained with anti-MCM2 antibody

Human Pancreas Adenocarcinoma stained with anti-MCM2 antibody

Human Stomach stained with anti-MCM2 antibody

Human Rectal Carcinoma stained with anti-MCM2 antibody

Human Prostate stained with anti-MCM2 antibody

Human Pancreas Adenocarcinoma stained with anti-MCM2 antibody

Human Stomach stained with anti-MCM2 antibody

Human Stomach Adenocarcinoma stained with anti-MCM2 antibody

Human Prostate Adenocarcinoma stained with anti-MCM2 antibody

Human Breast stained with anti-MCM2 antibody

Human Breast Ductal Carcinoma stained with anti-MCM2 antibody

Human Stomach Adenocarcinoma stained with anti-MCM2 antibody

Human Prostate Adenocarcinoma stained with anti-MCM2 antibody

Human Breast stained with anti-MCM2 antibody

Human Breast Ductal Carcinoma stained with anti-MCM2 antibody

Human Colon stained with anti-MCM2 antibody

Human Colon Adenocarcinoma stained with anti-MCM2 antibody

Human Skin stained with anti-MCM2 antibody

Human Skin Squamous Cell Carcinoma stained with anti-MCM2 antibody

Human Colon stained with anti-MCM2 antibody

Human Colon Adenocarcinoma stained with anti-MCM2 antibody

Human Skin stained with anti-MCM2 antibody

Human Skin Squamous Cell Carcinoma stained with anti-MCM2 antibody

Human Pancreas stained with anti-MCM2 antibody

Human Pancreas stained with anti-MCM2 antibody



Flow Cytometric Analysis

 

Flow cytometric analysis of rabbit anti-MCM2 (SP85) antibody in HeLa (green) compare to negative control of rabbit IgG (blue)
Flow cytometric analysis of rabbit anti-MCM2 (SP85) antibody in HeLa (green) compare to negative control of rabbit IgG (blue)



Western Blot Analysis

 

Western Blot analysis of rabbit anti-MCM2 (SP85) antibody
Western Blot analysis of rabbit anti-MCM2 (SP85) antibody

Product Details:

 

Technology

Rabbit Monoclonal

Clone Name

SP85

Application

IHC-P, WB, FACS

Species Reactivity

 

   Tested

Hu

   Predicted by homology

Bv, Dg, Fg, Ms, Rt

Isotype

Rabbit IgG

Immunogen

Synthetic peptide derived from internal region of human MCM2 protein.

Cellular Localization

Nucleus

Control Tissue

Rectal Carcinoma

Regulatory Rating

Research Use Only (RUO)

Entrez

4171

Storage Requirement

2-8°C

Target Molecular Weight

130 kDa

Formulation

Refer to Data Sheet