Rabbit Anti-Human MCM2 Monoclonal Antibody (Clone SP85)

For research use only. Not for use in diagnostics.

Product No.	Pack Size
06972179001	0.1 mL

Product No.	Pack Size
06972209001	1.0 mL

To order these products, please contact your Roche order management team.

Keywords: Antibodies, Rabbit Monoclonal

MCM2 (Mini chromosome maintenance protein 2) is involved in regulating DNA replication. MCM2 (also called CDCL1, mitotin and BM28), is a human nuclear protein that is crucial in the cell cycle, being involved in the onset of DNA replication and cell division. It is similar to members of the family of early S-phase proteins. Mincheva et al. (1994) mapped the gene to 3q21. From its localization, CDCL1 became a candidate for an oncogene affected by chromosomal breaks in acute myeloid leukemia (AML). **Please contact us for availability**

Figure above:
Human Rectal Carcinoma stained with anti-MCM2 antibody

Contents

Rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.

IHC Performance


Human Rectal Carcinoma stained with anti-MCM2 antibody	Human Prostate stained with anti-MCM2 antibody	Human Pancreas Adenocarcinoma stained with anti-MCM2 antibody	Human Stomach stained with anti-MCM2 antibody

Human Stomach Adenocarcinoma stained with anti-MCM2 antibody	Human Prostate Adenocarcinoma stained with anti-MCM2 antibody	Human Breast stained with anti-MCM2 antibody	Human Breast Ductal Carcinoma stained with anti-MCM2 antibody

Human Colon stained with anti-MCM2 antibody	Human Colon Adenocarcinoma stained with anti-MCM2 antibody	Human Skin stained with anti-MCM2 antibody	Human Skin Squamous Cell Carcinoma stained with anti-MCM2 antibody

Human Pancreas stained with anti-MCM2 antibody

Flow Cytometric Analysis

Flow cytometric analysis of rabbit anti-MCM2 (SP85) antibody in HeLa (green) compare to negative control of rabbit IgG (blue)

Western Blot Analysis

Western Blot analysis of rabbit anti-MCM2 (SP85) antibody

Product Details:

Technology	Rabbit Monoclonal
Clone Name	SP85
Application	IHC-P, WB, FACS
Species Reactivity
Tested	Hu
Predicted by homology	Bv, Dg, Fg, Ms, Rt
Isotype	Rabbit IgG
Immunogen	Synthetic peptide derived from internal region of human MCM2 protein.
Cellular Localization	Nucleus
Control Tissue	Rectal Carcinoma
Regulatory Rating	Research Use Only (RUO)
Entrez	4171
Storage Requirement	2-8°C
Target Molecular Weight	130 kDa
Formulation	Refer to Data Sheet

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