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Rabbit Anti-Human Myeloperoxidase Monoclonal Antibody (Clone SP72)

For research use only. Not for use in diagnostics.

Product No. Pack Size
06971652001 0.1 mL
Product No. Pack Size
06971695001 1.0 mL

To order these products, please contact your Roche order management team.

Myeloperoxidase (MPO) is an important enzyme used by granulocytes during phagocytic lysis of engulfed foreign particles. In normal tissues and in a variety of myeloproliferative disorders myeloid cells of both neutrophilic and eosinophilic types, at all stages of maturation, exhibit strong cytoplasmic reactivity for MPO. Erythroid precursors, megakaryocytes, lymphoid cells, mast cells, and plasma cells are nonreactive. MPO is not observed in epithelial tumors and sarcomas. MPO is positive in myeloid leukemias, but negative in lymphoid leukemias.

Figure above:
Human Tonsil stained with anti-Myeloperoxidase (MPO) antibody

Contents

Rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.

IHC Performance

 

Human Tonsil stained with anti-Myeloperoxidase (MPO) antibody

Human Spleen stained with anti-MPO antibody

Human Colon stained with anti-MPO antibody

Human Lymph Node stained with anti-MPO antibody

Human Tonsil stained with anti-Myeloperoxidase (MPO) antibody

Human Spleen stained with anti-MPO antibody

Human Colon stained with anti-MPO antibody

Human Lymph Node stained with anti-MPO antibody

Human Bone Marrow stained with anti-MPO antibody

Human Lung stained with anti-MPO antibody

Human Lung Squamous Cell Carcinoma stained with anti-MPO antibody

Human Colon Adenocarcinoma stained with anti-MPO antibody

Human Bone Marrow stained with anti-MPO antibody

Human Lung stained with anti-MPO antibody

Human Lung Squamous Cell Carcinoma stained with anti-MPO antibody

Human Colon Adenocarcinoma stained with anti-MPO antibody

Human Lung Adenocarcinoma stained with anti-MPO antibody

Human Stomach Adenocarcinoma stained with anti-MPO antibody

Human Lung Adenocarcinoma stained with anti-MPO antibody

Human Stomach Adenocarcinoma stained with anti-MPO antibody

Product Details:

 

Technology

Rabbit Monoclonal

Clone Name

SP72

Application

IHC-P

Species Reactivity

 

   Tested

Hu

   Predicted by homology

 

Isotype

Rabbit IgG

Immunogen

Synthetic peptide corresponding to C-terminus of human myeloperoxidase protein.

Cellular Localization

Cytoplasm

Control Tissue

Tonsil

Regulatory Rating

Research Use Only (RUO)

Entrez

4353

Storage Requirement

2-8°C

Target Molecular Weight

84 kDa

Formulation

Refer to Data Sheet