Rabbit Anti-Human Myeloperoxidase Monoclonal Antibody (Clone SP72)
For research use only. Not for use in diagnostics.
Product No. | Pack Size |
---|---|
06971652001 | 0.1 mL |
Product No. | Pack Size |
---|---|
06971695001 | 1.0 mL |
To order these products, please contact your Roche order management team.
Myeloperoxidase (MPO) is an important enzyme used by granulocytes during phagocytic lysis of engulfed foreign particles. In normal tissues and in a variety of myeloproliferative disorders myeloid cells of both neutrophilic and eosinophilic types, at all stages of maturation, exhibit strong cytoplasmic reactivity for MPO. Erythroid precursors, megakaryocytes, lymphoid cells, mast cells, and plasma cells are nonreactive. MPO is not observed in epithelial tumors and sarcomas. MPO is positive in myeloid leukemias, but negative in lymphoid leukemias.
Figure above:
Human Tonsil stained with anti-Myeloperoxidase (MPO) antibody
Contents
Rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.
IHC Performance
Human Tonsil stained with anti-Myeloperoxidase (MPO) antibody |
Human Spleen stained with anti-MPO antibody |
Human Colon stained with anti-MPO antibody |
Human Lymph Node stained with anti-MPO antibody |
Human Bone Marrow stained with anti-MPO antibody |
Human Lung stained with anti-MPO antibody |
Human Lung Squamous Cell Carcinoma stained with anti-MPO antibody |
Human Colon Adenocarcinoma stained with anti-MPO antibody |
Human Lung Adenocarcinoma stained with anti-MPO antibody |
Human Stomach Adenocarcinoma stained with anti-MPO antibody |
Product Details:
Technology |
Rabbit Monoclonal |
Clone Name |
SP72 |
Application |
IHC-P |
Species Reactivity |
|
Tested |
Hu |
Predicted by homology |
|
Isotype |
Rabbit IgG |
Immunogen |
Synthetic peptide corresponding to C-terminus of human myeloperoxidase protein. |
Cellular Localization |
Cytoplasm |
Control Tissue |
Tonsil |
Regulatory Rating |
Research Use Only (RUO) |
Entrez |
4353 |
Storage Requirement |
2-8°C |
Target Molecular Weight |
84 kDa |
Formulation |
Refer to Data Sheet |