Rabbit Anti-Human p53 Monoclonal Antibody (Clone SP161)
For research use only. Not for use in diagnostics.
| Product No. | Pack Size |
|---|---|
| 06974988001 | 0.1 mL |
| Product No. | Pack Size |
|---|---|
| 06975011001 | 1.0 mL |
To order these products, please contact your Roche order management team.
p53 is a tumor suppressor gene expressed in a wide variety of tissue types and is involved in regulating cell growth, replication, and apoptosis. It binds to mdm2, SV40 T antigen and human papilloma virus E6 protein. p53 senses DNA damage and possibly facilitates repair. Mutation involving p53 is found in a wide variety of malignant tumors, including breast, ovarian, bladder, colon, lung, and melanoma.
Figure above:
Human Colon Adenocarcinoma stained with anti-p53 antibody
Contents
Rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.
IHC Performance
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Human B-cell lymphoma stained with anti-P53 antibody |
Human Bladder Transitional Cell Carcinoma stained with anti-P53 antibody |
Human Breast Ductal Carcinoma stained with anti-P53 antibody |
Human Colon Adenocarcinoma stained with anti-p53 antibody |
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Human Lung Squamous Cell Carcinoma stained with anti-P53 antibody |
Human Ovarian Adenocarcinoma stained with anti-P53 antibody |
Human Stomach Adenocarcinoma stained with anti-P53 antibody |
Product Details:
Technology |
Rabbit Monoclonal |
Clone Name |
SP161 |
Application |
IHC-P |
Species Reactivity |
|
Tested |
Hu |
Predicted by homology |
Bv, Dg, Hm, Ms, Pg, Rb, Rt |
Isotype |
Rabbit IgG |
Immunogen |
Recombinant human full length wild type p53 protein. |
Cellular Localization |
Nucleus |
Control Tissue |
Colon Carcinoma |
Regulatory Rating |
Research Use Only (RUO) |
Entrez |
7157 |
Storage Requirement |
2-8°C |
Target Molecular Weight |
53 kDa |
Formulation |
Refer to Data Sheet |
Associated Products
Instructions for Use (IFU)
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