Rabbit Anti-Human p53 Monoclonal Antibody (Clone SP161)

For research use only. Not for use in diagnostics.

Product No.	Pack Size
06974988001	0.1 mL

Product No.	Pack Size
06975011001	1.0 mL

To order these products, please contact your Roche order management team.

Keywords: Antibodies, Rabbit Monoclonal

p53 is a tumor suppressor gene expressed in a wide variety of tissue types and is involved in regulating cell growth, replication, and apoptosis. It binds to mdm2, SV40 T antigen and human papilloma virus E6 protein. p53 senses DNA damage and possibly facilitates repair. Mutation involving p53 is found in a wide variety of malignant tumors, including breast, ovarian, bladder, colon, lung, and melanoma.

Figure above:
Human Colon Adenocarcinoma stained with anti-p53 antibody

Contents

Rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.

IHC Performance


Human B-cell lymphoma stained with anti-P53 antibody	Human Bladder Transitional Cell Carcinoma stained with anti-P53 antibody	Human Breast Ductal Carcinoma stained with anti-P53 antibody	Human Colon Adenocarcinoma stained with anti-p53 antibody

Human Lung Squamous Cell Carcinoma stained with anti-P53 antibody	Human Ovarian Adenocarcinoma stained with anti-P53 antibody	Human Stomach Adenocarcinoma stained with anti-P53 antibody

Product Details:

Technology	Rabbit Monoclonal
Clone Name	SP161
Application	IHC-P
Species Reactivity
Tested	Hu
Predicted by homology	Bv, Dg, Hm, Ms, Pg, Rb, Rt
Isotype	Rabbit IgG
Immunogen	Recombinant human full length wild type p53 protein.
Cellular Localization	Nucleus
Control Tissue	Colon Carcinoma
Regulatory Rating	Research Use Only (RUO)
Entrez	7157
Storage Requirement	2-8°C
Target Molecular Weight	53 kDa
Formulation	Refer to Data Sheet

Associated Products

Rabbit Anti-Human p53 Monoclonal Antibody (Clone SP5) Read more

Rabbit Anti-Human p57 Monoclonal Antibody (Clone SP118) Read more

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