Rabbit Anti-Human PD-1/CD279 Monoclonal Antibody (Clone SP269)
For research use only. Not for use in diagnostics.
| Product No. | Pack Size |
|---|---|
| 07489161001 | 0.1 mL |
| Product No. | Pack Size |
|---|---|
| 07489218001 | 1.0 mL |
To order these products, please contact your Roche order management team.
Programmed cell death protein 1 (PD-1), as known as CD279, is a member of CD28/CTLA-4 family of T cell regulators. It is expressed on the surface of activated T cells, B cells, and macrophages as a negative regulator for immune responses. The binding of PD-1 with its ligands PDL1 and PDL2 on T cells, monocytes, and some tumor cells can trigger inhibition of T-cell function.
Figure above:
Human tonsil stained with anti-PD-1 antibody
Contents
Rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.
IHC Performance
|
Human Tonsil stained with anti-PD-1 antibody |
Flow Cytometric Analysis
Flow cytometric analysis of rabbit anti-PD-1 (SP269) antibody in THP- 1 cells (green) compare to negative control of rabbit IgG (blue)
Product Details:
Technology |
Rabbit Monoclonal |
Clone Name |
SP269 |
Application |
IHC-P, FACS |
Species Reactivity |
|
Tested |
Hu |
Predicted by homology |
N/A |
Isotype |
Rabbit IgG |
Immunogen |
Synthetic peptide derived from the N-terminus of human PD-1 protein. |
Cellular Localization |
Membrane |
Control Tissue |
Tonsil |
Regulatory Rating |
Research Use Only (RUO) |
Entrez |
5133 |
Storage Requirement |
2-8°C |
Target Molecular Weight |
32 kDa |
Formulation |
Refer to Data Sheet |
Associated Products
Instructions for Use (IFU)
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