Rabbit Anti-Human PD-1/CD279 Monoclonal Antibody (Clone SP269)

Programmed cell death protein 1 (PD-1), as known as CD279, is a member of CD28/CTLA-4 family of T cell regulators. It is expressed on the surface of activated T cells, B cells, and macrophages as a negative regulator for immune responses. The binding of PD-1 with its ligands PDL1 and PDL2 on T cells, monocytes, and some tumor cells can trigger inhibition of T-cell function.

Figure above:
Human tonsil stained with anti-PD-1 antibody

Contents

Rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.