Rabbit Anti-Human PTEN Monoclonal Antibody (Clone SP170)
For research use only. Not for use in diagnostics.
| Product No. | Pack Size |
|---|---|
| 06771050001 | 0.1 mL |
| Product No. | Pack Size |
|---|---|
| 06771076001 | 1.0 mL |
To order these products, please contact your Roche order management team.
Phosphatidylinositol-3, 4, 5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase (PTEN) is a tumor suppressor and a member in the PI3K/PTEN/AKT pathway. PTEN is a phosphatase with dual specificity to slow cell growth and antagonize the growth promoting activities from HER protein kinases. The defects of PTEN, mostly around the C-terminus of PTEN, have been implicated in many human cancers and diseases. Therefore, antibody to the N terminus will not be able to detect most of the PTEN protein loss. **Please contact us for availability**
Figure above:
Human prostate adenocarcinoma stained with anti-PTEN antibody
Contents
Rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.
IHC Performance
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Human Cervical Squamous Cell Carcinoma stained with anti-PTEN antibody |
Human Colon Adenocarcinoma stained with anti-PTEN antibody |
Human Lung Squamous Cell Carcinoma stained with anti-PTEN antibody |
Human Ovarian Carcinoma stained with anti-PTEN antibody |
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Human Ovary stained with anti-PTEN antibody |
Human Prostate Adencarcinoma stained with anti-PTEN antibody |
Human Prostate Adencarcinoma stained with anti-PTEN antibody |
Human Prostate adenocarcinoma stained with anti-PTEN antibody |
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Human Prostate Adenocarcinoma stained with anti-PTEN antibody |
Human Prostate stained with anti-PTEN antibody |
Human Stomach Adenocarcinoma stained with anti-PTEN antibody |
Flow Cytometric Analysis
Flow cytometric analysis of rabbit anti-PTEN (SP170) antibody in A431 (green) compare to negative control of rabbit IgG (blue)
Western Blot Analysis
Western Blot analysis of MCF-7 cell lysate with PTEN antibody
Product Details:
Technology |
Rabbit Monoclonal |
Clone Name |
SP170 |
Application |
IHC-P, WB, FACS |
Species Reactivity |
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Tested |
Hu |
Predicted by homology |
Dg, Ms |
Isotype |
Rabbit IgG |
Immunogen |
Synthetic peptide close to the N-terminus of human PTEN protein. |
Cellular Localization |
Cytoplasm |
Control Tissue |
Prostate Adenocarcinoma |
Regulatory Rating |
Research Use Only (RUO) |
Entrez |
5728 |
Storage Requirement |
2-8°C |
Target Molecular Weight |
54 kDa |
Formulation |
Refer to Data Sheet |
Associated Products
Instructions for Use (IFU)
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