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Rabbit Anti-Human S6 Ribosomal Protein (Phospho S240/244) Monoclonal Antibody (Clone SP45)

For research use only. Not for use in diagnostics.

Product No. Pack Size
05498597001 0.1 mL
Product No. Pack Size
05498619001 1.0 mL

To order these products, please contact your Roche order management team.

40S ribosomal protein S6 (also known as RPS6) is a ~31 kDa substrate of p70 S6 kinase (p70S6K) and a major component of translational machinery involved in protein synthesis, cell growth, proliferation, and metabolism. RPS6 undergoes phosphorylation on multiple serines in the carboxyl terminal region in the order 236-->235-->240-->244-->247, due to the positions of these amino acid residues on the alpha-helix. Hyperphosphorylation of RPS6 stimulates protein synthesis that mediates progression through the cell cycle. **Please contact us for availability**

Figure above:
Human Breast Carcinoma stained with anti-S6 Ribosomal (Phospho S240/244) antibody

Contents

Rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.

IHC Performance

 


Human Breast Carcinoma stained with anti-S6 Ribosomal (Phospho S240/244) antibody

Product Details:

 

Technology

Rabbit Monoclonal

Clone Name

SP45

Application

IHC-P

Species Reactivity

 

   Tested

Hu

   Predicted by homology

Bv, Ck, Dg, Fg, Ms, Pg, Rb, Rt

Isotype

Rabbit IgG

Immunogen

Synthetic peptide derived from the region of human S6 ribosomal that contains phosphorylated serines 240 and 244.

Cellular Localization

Cytoplasm

Control Tissue

Breast Carcinoma

Regulatory Rating

Research Use Only (RUO)

Entrez

180460

Storage Requirement

2-8°C

Target Molecular Weight

31 kDa

Formulation

Refer to Data Sheet