Rabbit Anti-Human SOX-10 Monoclonal Antibody (Clone SP267)

For research use only. Not for use in diagnostics.

Product No.	Pack Size
07489242001	0.1 mL

Product No.	Pack Size
07489277001	1.0 mL

To order these products, please contact your Roche order management team.

Keywords: Antibodies, Rabbit Monoclonal

SOX-10 is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. SOX-10 is predominantly found in oligodendrocytes, peripheral glial cells, melanocytes and adult neural crest stem cell populations. SOX-10 is up-regulated in melanoma, glioma, Schwannoma, neurofibroma, pheochromocytoma, and lung carcinoid tumor.

Figure above:
Human melanoma stained with anti-SOX-10 antibody

Contents

Rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.

IHC Performance

Human Melanoma stained with anti-SOX-10 antibody

Western Blot Analysis

Western Blot analysis of A375 cell lysate with SOX-10 antibody

Product Details:

Technology	Rabbit Monoclonal
Clone Name	SP267
Application	IHC-P, WB
Species Reactivity
Tested	Hu
Predicted by homology	Ck, Ms, Pg, Rt
Isotype	Rabbit IgG
Immunogen	Synthetic peptide near the C-terminus of the human SOX-10 protein.
Cellular Localization	Nucleus
Control Tissue	Melanoma
Regulatory Rating	Research Use Only (RUO)
Entrez	6663
Storage Requirement	2-8°C
Target Molecular Weight	56 kDa
Formulation	Refer to Data Sheet

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