Rabbit Anti-Human SOX-10 Monoclonal Antibody (Clone SP267)
For research use only. Not for use in diagnostics.
| Product No. | Pack Size |
|---|---|
| 07489242001 | 0.1 mL |
| Product No. | Pack Size |
|---|---|
| 07489277001 | 1.0 mL |
To order these products, please contact your Roche order management team.
SOX-10 is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. SOX-10 is predominantly found in oligodendrocytes, peripheral glial cells, melanocytes and adult neural crest stem cell populations. SOX-10 is up-regulated in melanoma, glioma, Schwannoma, neurofibroma, pheochromocytoma, and lung carcinoid tumor.
Figure above:
Human melanoma stained with anti-SOX-10 antibody
Contents
Rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.
IHC Performance
|
Human Melanoma stained with anti-SOX-10 antibody |
Western Blot Analysis
Western Blot analysis of A375 cell lysate with SOX-10 antibody
Product Details:
Technology |
Rabbit Monoclonal |
Clone Name |
SP267 |
Application |
IHC-P, WB |
Species Reactivity |
|
Tested |
Hu |
Predicted by homology |
Ck, Ms, Pg, Rt |
Isotype |
Rabbit IgG |
Immunogen |
Synthetic peptide near the C-terminus of the human SOX-10 protein. |
Cellular Localization |
Nucleus |
Control Tissue |
Melanoma |
Regulatory Rating |
Research Use Only (RUO) |
Entrez |
6663 |
Storage Requirement |
2-8°C |
Target Molecular Weight |
56 kDa |
Formulation |
Refer to Data Sheet |
Instructions for Use (IFU)
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