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Rabbit Anti-Human TROP-2 Monoclonal Antibody (Clone SP293)

For research use only. Not for use in diagnostics.

Product No. Pack Size
07747144001 0.1 mL
Product No. Pack Size
07747179001 1.0 mL

To order these products, please contact your Roche order management team.

Tumor-associated calcium signal transducer 2 (TROP-2) is a transmembrane glycoprotein of tumor-associated calcium signal transducer (TACSTD) gene family. It is an EpCAM-like molecule and it is expressed in squamous, cuboidal, and columnar epithelium of normal organs. TROP-2 is overexpressed in various types of epithelial carcinomas from lung, breast, stomach, ovary, cervix, colon and pancreas.

Figure above:
Human tonsil stained with anti-TROP-2 (SP293) antibody

Contents

Rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.

IHC Performance

 

Human Bladder stained with anit-TROP-2 antibody.

Human Bladder transitional cell carcinoma stained with anit-TROP-2 antibody

Human Esophagus stained with anit-TROP-2 antibody.

Human Lung squamous cell carcinoma stained with anit-TROP-2 antibody

Human Bladder stained with anit-TROP-2 antibody.

Human Bladder transitional cell carcinoma stained with anit-TROP-2 antibody

Human Esophagus stained with anit-TROP-2 antibody.

Human Lung squamous cell carcinoma stained with anit-TROP-2 antibody

Human Ovarian adenocarcinoma stained with anit-TROP-2 antibody

Human Prostate adenocarcinoma stained with anit-TROP-2 antibody

Human Prostate adenocarcinoma stained with anit-TROP-2 antibody

Human Skin squamous cell carcinoma stained with anit-TROP-2 antibody

Human Ovarian adenocarcinoma stained with anit-TROP-2 antibody

Human Prostate adenocarcinoma stained with anit-TROP-2 antibody

Human Prostate adenocarcinoma stained with anit-TROP-2 antibody

Human Skin squamous cell carcinoma stained with anit-TROP-2 antibody

Human Skin stained with anit-TROP-2 antibody.

Human Tonsil stained with anti-TROP-2 (SP293) antibody

Human Skin stained with anit-TROP-2 antibody.

Human Tonsil stained with anti-TROP-2 (SP293) antibody



Flow Cytometric Analysis

 

Flow cytometric analysis of rabbit anti-TROP-2 (SP293) antibody in SKBR3 cells (green) compare to negative control of rabbit IgG (blue)

Flow cytometric analysis of rabbit anti-TROP-2 (SP293) antibody in SKBR3 cells (green) compare to negative control of rabbit IgG (blue)



Western Blot Analysis

 

Western Blot analysis of SKBR3 cell lysate with anti-TROP-2 (SP293) antibody

Western Blot analysis of SKBR3 cell lysate with anti-TROP-2 (SP293) antibody

Product Details:

 

Technology

Rabbit Monoclonal

Clone Name

SP293

Application

IHC-P, WB, FACS

Species Reactivity

 

   Tested

Hu

   Predicted by homology

Ms

Isotype

Rabbit IgG

Immunogen

Synthetic peptide derived from the C-terminus of human TROP-2 protein.

Cellular Localization

Membrane

Control Tissue

Tonsil

Regulatory Rating

Research Use Only (RUO)

Entrez

4070

Storage Requirement

2-8°C

Target Molecular Weight

33 kDa

Formulation

Refer to Data Sheet