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Rabbit Anti-Human TROP-2 Monoclonal Antibody (Clone SP294)

For research use only. Not for use in diagnostics.

Product No. Pack Size
07747608001 0.1 mL
Product No. Pack Size
07747624001 1.0 mL

To order these products, please contact your Roche order management team.

Tumor-associated calcium signal transducer 2 (TROP-2) is a transmembrane glycoprotein of tumor-associated calcium signal transducer (TACSTD) gene family. It is an EpCAM-like molecule and it is expressed in squamous, cuboidal, and columnar epithelium of normal organs. TROP-2 is overexpressed in various types of epithelial carcinomas from lung, breast, stomach, ovary, cervix, colon and pancreas.

Figure above:
Human skin stained with anti-TROP-2 antibody

Contents

Rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.

 

IHC Performance

 

Human Bladder stained with anti-TROP-2 antibody

Human Bladder TCC stained with anti-TROP-2 antibody

Human Breast ductal cell carcinoma stained with anti-TROP-2 antibody

Human Breast stained with anti-TROP-2 antibody

Human Bladder stained with anti-TROP-2 antibody

Human Bladder TCC stained with anti-TROP-2 antibody

Human Breast ductal cell carcinoma stained with anti-TROP-2 antibody

Human Breast stained with anti-TROP-2 antibody

Human Cervical squamous cell carcinoma stained with anti-TROP-2 antibody

Human Cervix stained with anti-TROP-2 antibody

Human Lung squamous cell carcinoma stained with anti-TROP-2 antibody

Human Lung stained with anti-TROP-2 antibody

Human Cervical squamous cell carcinoma stained with anti-TROP-2 antibody

Human Cervix stained with anti-TROP-2 antibody

Human Lung squamous cell carcinoma stained with anti-TROP-2 antibody

Human Lung stained with anti-TROP-2 antibody

Human Pancreatic adenocarcinoma stained with anti-TROP-2 antibody

Human Prostate adenocarcinoma stained with anti-TROP-2 antibody

Human Prostate stained with anti-TROP-2 antibody

Human Skin squamous cell carcinoma stained with anti-TROP-2 antibody

Human Pancreatic adenocarcinoma stained with anti-TROP-2 antibody

Human Prostate adenocarcinoma stained with anti-TROP-2 antibody

Human Prostate stained with anti-TROP-2 antibody

Human Skin squamous cell carcinoma stained with anti-TROP-2 antibody

Human Skin stained with anti-TROP-2 antibody

Human Tonsil stained with anti-TROP-2 (SP294) antibody

Human Skin stained with anti-TROP-2 antibody

Human Tonsil stained with anti-TROP-2 (SP294) antibody



Western Blot Analysis

 

Western blot analysis of SKBR3 cell lysate with anti-TROP-2 (SP294) antibody

Western blot analysis of SKBR3 cell lysate with anti-TROP-2 (SP294) antibody


Product Details:

 

Technology

Rabbit Monoclonal

Clone Name

SP294

Application

IHC-P, WB

Species Reactivity

 

   Tested

Hu

   Predicted by homology

Ms

Isotype

Rabbit IgG

Immunogen

Synthetic peptide derived from the internal region of human TROP-2 protein.

Cellular Localization

Membrane

Control Tissue

Tonsil

Regulatory Rating

Research Use Only (RUO)

Entrez

4070

Storage Requirement

2-8°C

Target Molecular Weight

33 kDa

Formulation

Refer to Data Sheet