Rabbit Anti-Human TROP-2 Monoclonal Antibody (Clone SP294)
For research use only. Not for use in diagnostics.
Product No. | Pack Size |
---|---|
07747608001 | 0.1 mL |
Product No. | Pack Size |
---|---|
07747624001 | 1.0 mL |
To order these products, please contact your Roche order management team.
Tumor-associated calcium signal transducer 2 (TROP-2) is a transmembrane glycoprotein of tumor-associated calcium signal transducer (TACSTD) gene family. It is an EpCAM-like molecule and it is expressed in squamous, cuboidal, and columnar epithelium of normal organs. TROP-2 is overexpressed in various types of epithelial carcinomas from lung, breast, stomach, ovary, cervix, colon and pancreas.
Figure above:
Human skin stained with anti-TROP-2 antibody
Contents
Rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.
IHC Performance
Human Bladder stained with anti-TROP-2 antibody |
Human Bladder TCC stained with anti-TROP-2 antibody |
Human Breast ductal cell carcinoma stained with anti-TROP-2 antibody |
Human Breast stained with anti-TROP-2 antibody |
Human Cervical squamous cell carcinoma stained with anti-TROP-2 antibody |
Human Cervix stained with anti-TROP-2 antibody |
Human Lung squamous cell carcinoma stained with anti-TROP-2 antibody |
Human Lung stained with anti-TROP-2 antibody |
Human Pancreatic adenocarcinoma stained with anti-TROP-2 antibody |
Human Prostate adenocarcinoma stained with anti-TROP-2 antibody |
Human Prostate stained with anti-TROP-2 antibody |
Human Skin squamous cell carcinoma stained with anti-TROP-2 antibody |
Human Skin stained with anti-TROP-2 antibody |
Human Tonsil stained with anti-TROP-2 (SP294) antibody |
Western Blot Analysis
Western blot analysis of SKBR3 cell lysate with anti-TROP-2 (SP294) antibody
Product Details:
Technology |
Rabbit Monoclonal |
Clone Name |
SP294 |
Application |
IHC-P, WB |
Species Reactivity |
|
Tested |
Hu |
Predicted by homology |
Ms |
Isotype |
Rabbit IgG |
Immunogen |
Synthetic peptide derived from the internal region of human TROP-2 protein. |
Cellular Localization |
Membrane |
Control Tissue |
Tonsil |
Regulatory Rating |
Research Use Only (RUO) |
Entrez |
4070 |
Storage Requirement |
2-8°C |
Target Molecular Weight |
33 kDa |
Formulation |
Refer to Data Sheet |